PRO_ID
PRO identifier, mandatory.
Object_term
Name of the PRO term, Mandatory, cardinality 1.
Object_synonym
Other names by which the described object is known, Optional field. Cardinality 0, 1 or >1. Separated by | (e.g. smad5beta|smad5b).
Modifier
Modifiers are used within an annotation to modify a relation between a PRO term (protein) and another term (which can be internal or external to PRO). It includes the qualifiers used by GO: NOT, and contributes_to. And also includes decreased, increased and altered (see table 2 below for more information). This field is not mandatory; cardinality 0, 1, >1; for cardinality >1 use a pipe to separate entries (e.g. NOT|contributes_to).
Relation
Relation to the corresponding annotation. For the list of relations used in PRO see table 3 below. Mandatory, cardinality 1.
Ontology_ID
ID for the corresponding annotation. Mandatory, cardinality 1.
Ontology_term
Term name for the corresponding ontology ID. Mandatory, cardinality 1.
Relative_to
Contains a PRO identifier. Modifiers increased, decreased and altered require an entry in this column to indicate what the change is relative to.
Interaction_with
To indicate binding partner. For GO component complex and GO function protein binding. If possible indicate the most exact protein object by using PRO ID. If part of a complex please add the GO ID for the corresponding one. Not mandatory, cardinality 0 or 1.
Evidence_source
Pubmed ID or database source for the evidence. Mandatory, cardinality 1. (or >1?)
Evidence_code
At the ProEvo level, the evidence code is ISS (inferred by sequence and/or structural similarity) At the protein form level only experimental evidence codes are allowed. If no expertise in evidence code assignation please use EXP (experimental evidence) as a general code. For GO term protein binding, the evidence code should be IPI. From GOA source: see the GO evidence code guide for the list of valid evidence codes for GO annotations. This field is mandatory for GO terms, cardinality 1.
Taxon
Taxon identifier for the species that the annotation is extracted from. Related to column 9. Not mandatory, cardinality 0 or 1.
Inferred_from
This field is used only for certain types of evidence code: IPI and ISS for PRO. Cardinality 0, 1, >1; for cardinality >1 use a pipe to separate entries (e.g. PANTHER:PTHR13703:SF17|PIRSF:PIRSF500500).
DB_ID
GOA Source:one or more unique identifiers for a single source cited as an authority for the attribution of the ontology ID to the DB_Object_ID. This may be a literature reference or a database record. The syntax is DB:accession_number.
Date
From GOA source: Date on which the annotation was made; format is YYYY-MM-DD this field is mandatory, cardinality 1.
Assigned_by
The database which made the annotation. This field is mandatory, cardinality 1. Format: Source DB:curator initials.
Comments
Curator comment for some annotations.
E3 ubiquitin ligase SFC complex Skp1 subunit
ubiquitin-dependent protein catabolic process
DNA-binding transcription factor activity
regulation of DNA-templated transcription
transforming growth factor-beta receptor type II
transforming growth factor beta receptor signaling pathway
regulation of cell population proliferation
TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I (PTHR23255:SF15)
transforming growth factor beta receptor activity, type I
cell surface receptor protein serine/threonine kinase signaling pathway
TGF-beta superfamily receptor type-2 with activin receptor domain
transmembrane receptor protein serine/threonine kinase activity
anti-Muellerian hormone type II receptor
extracellular matrix structural constituent
cyclin-dependent protein serine/threonine kinase inhibitor activity
regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell population proliferation
negative regulation of activin receptor signaling pathway
HECT domain-containing E3 ubiquitin-protein ligase with WW domains
positive regulation of chemokine production
negative regulation of BMP signaling pathway
RHO-ASSOCIATED, COILED-COIL CONTAINING PROTEIN KINASE (PTHR22988:SF3)
protein serine/threonine kinase activity
sara-type zinc finger FYVE domain-containing protein
transcription adapter with TAZ, KIX and bromo-domains
bone morphogenetic protein receptor type II
class B basic helix-loop-helix protein 24
class B basic helix-loop-helix protein 26
negative regulation of DNA-templated transcription
class B basic helix-loop-helix protein 25
class B basic helix-loop-helix protein 27
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
transforming growth factor beta receptor binding
TGF-beta receptor type-2 sequence variant L308P (human)
TGF-beta receptor type-2 sequence variant 1 (human)
transforming growth factor beta receptor activity, type II
TGF-beta receptor type-2 sequence variant R460H (human)
TGF-beta receptor type-2 sequence variant 10 (human)
TGF-beta receptor type-2 sequence variant R460C (human)
TGF-beta receptor type-2 sequence variant 11 (human)
TGF-beta receptor type-2 sequence variant E526Q (human)
TGF-beta receptor type-2 sequence variant 12 (human)
TGF-beta receptor type-2 sequence variant R528C (human)
TGF-beta receptor type-2 sequence variant 13 (human)
TGF-beta receptor type-2 sequence variant R528H (human)
TGF-beta receptor type-2 sequence variant 14 (human)
TGF-beta receptor type-2 sequence variant R537C (human)
TGF-beta receptor type-2 sequence variant 15 (human)
TGF-beta receptor type-2 sequence variant G357W (human)
TGF-beta receptor type-2 sequence variant 16 (human)
TGF-beta receptor type-2 sequence variant T315M (human)
TGF-beta receptor type-2 sequence variant 2 (human)
positive regulation of cell population proliferation
TGF-beta receptor type-2 sequence variant Y336N (human)
TGF-beta receptor type-2 sequence variant 3 (human)
TGF-beta receptor type-2 sequence variant A355P (human)
TGF-beta receptor type-2 sequence variant 4 (human)
TGF-beta receptor type-2 sequence variant V387M (human)
TGF-beta receptor type-2 sequence variant 5 (human)
TGF-beta receptor type-2 sequence variant N435S (human)
TGF-beta receptor type-2 sequence variant 6 (human)
TGF-beta receptor type-2 sequence variant V447A (human)
TGF-beta receptor type-2 sequence variant 7 (human)
TGF-beta receptor type-2 sequence variant S449F (human)
TGF-beta receptor type-2 sequence variant 8 (human)
TGF-beta receptor type-2 sequence variant L452M (human)
TGF-beta receptor type-2 sequence variant 9 (human)
TGF-beta receptor-regulated smad protein
anti-Muellerian hormone type-2 receptor sequence variant R54C (human)
anti-Muellerian hormone type-2 receptor sequence variant 1 (human)
anti-Muellerian hormone type-2 receptor sequence variant G142V (human)
anti-Muellerian hormone type-2 receptor sequence variant 2 (human)
anti-Muellerian hormone type-2 receptor sequence variant H282Q (human)
anti-Muellerian hormone type-2 receptor sequence variant 3 (human)
anti-Muellerian hormone type-2 receptor sequence variant R406Q (human)
anti-Muellerian hormone type-2 receptor sequence variant 4 (human)
anti-Muellerian hormone type-2 receptor sequence variant D426G (human)
anti-Muellerian hormone type-2 receptor sequence variant 5 (human)
anti-Muellerian hormone type-2 receptor sequence variant V458A (human)
anti-Muellerian hormone type-2 receptor sequence variant 6 (human)
anti-Muellerian hormone type-2 receptor sequence variant D491H (human)
anti-Muellerian hormone type-2 receptor sequence variant 7 (human)
anti-Muellerian hormone type-2 receptor sequence variant R504C (human)
anti-Muellerian hormone type-2 receptor sequence variant 8 (human)
tumor necrosis factor ligand superfamily member 6
negative regulation of signal transduction
negative regulation of transforming growth factor beta receptor signaling pathway
small GTPase-mediated signal transduction
zinc finger FYVE domain-containing protein 9
mothers against decapentaplegic homolog-interacting protein
BMP receptor type-1A sequence variant Y62D (human)
BMP receptor type-1A sequence variant 1 (human)
BMP receptor type-1A sequence variant C82Y (human)
BMP receptor type-1A sequence variant 2 (human)
BMP receptor type-1A sequence variant C124R (human)
BMP receptor type-1A sequence variant 3 (human)
BMP receptor type-1A sequence variant C130R (human)
BMP receptor type-1A sequence variant 4 (human)
BMP receptor type-1A sequence variant A338D (human)
BMP receptor type-1A sequence variant 5 (human)
BMP receptor type-1A sequence variant C376Y (human)
BMP receptor type-1A sequence variant 6 (human)
BMP receptor type-1A sequence variant R443C (human)
BMP receptor type-1A sequence variant 7 (human)
BMP receptor type-1A sequence variant M470T (human)
BMP receptor type-1A sequence variant 8 (human)
BMP receptor type-1B sequence variant I200K (human)
BMP receptor type-1B sequence variant 1 (human)
BMP receptor type-1B sequence variant R486W (human)
BMP receptor type-1B sequence variant 2 (human)
BMP receptor type-2 sequence variant C60Y (human)
BMP receptor type-2 sequence variant 1 (human)
BMP receptor type-2 sequence variant D485G (human)
BMP receptor type-2 sequence variant 10 (human)
BMP receptor type-2 sequence variant R491Q (human)
BMP receptor type-2 sequence variant 11 (human)
BMP receptor type-2 sequence variant R491W (human)
BMP receptor type-2 sequence variant 12 (human)
BMP receptor type-2 sequence variant K512T (human)
BMP receptor type-2 sequence variant 13 (human)
BMP receptor type-2 sequence variant N519K (human)
BMP receptor type-2 sequence variant 14 (human)
BMP receptor type-2 sequence variant C117Y (human)
BMP receptor type-2 sequence variant 2 (human)
BMP receptor type-2 sequence variant C118W (human)
BMP receptor type-2 sequence variant 3 (human)
BMP receptor type-2 sequence variant C123R (human)
BMP receptor type-2 sequence variant 4 (human)
BMP receptor type-2 sequence variant C123S (human)
BMP receptor type-2 sequence variant 5 (human)
BMP receptor type-2 sequence variant E224D (human)
BMP receptor type-2 sequence variant 6 (human)
BMP receptor type-2 sequence variant C347Y (human)
BMP receptor type-2 sequence variant 7 (human)
BMP receptor type-2 sequence variant C420R (human)
BMP receptor type-2 sequence variant 8 (human)
BMP receptor type-2 sequence variant C483R (human)
BMP receptor type-2 sequence variant 9 (human)
glioblastoma-derived T-cell suppressor factor
TGF-beta receptor type-1 sequence variant T200I (human)
TGF-beta receptor type-1 sequence variant 1 (human)
TGF-beta receptor type-1 sequence variant 10 (human)
TGF-beta receptor type-1 sequence variant 11 (human)
TGF-beta receptor type-1 sequence variant K232E (human)
TGF-beta receptor type-1 sequence variant 2 (human)
TGF-beta receptor type-1 sequence variant S241L (human)
TGF-beta receptor type-1 sequence variant 3 (human)
TGF-beta receptor type-1 sequence variant N267H (human)
TGF-beta receptor type-1 sequence variant 4 (human)
TGF-beta receptor type-1 sequence variant M318R (human)
TGF-beta receptor type-1 sequence variant 5 (human)
TGF-beta receptor type-1 sequence variant D400G (human)
TGF-beta receptor type-1 sequence variant 6 (human)
TGF-beta receptor type-1 sequence variant R487P (human)
TGF-beta receptor type-1 sequence variant 7 (human)
TGF-beta receptor type-1 sequence variant R487E (human)
TGF-beta receptor type-1 sequence variant 8 (human)
TGF-beta receptor type-1 sequence variant R487W (human)
TGF-beta receptor type-1 sequence variant 9 (human)
activin receptor type-1 sequence variant R206H (human)
activin receptor type-1 sequence variant 1 (human)
activin receptor type-2B sequence variant R40H (human)
activin receptor type-2B sequence variant 1 (human)
activin receptor type-2B sequence variant V494I (human)
activin receptor type-2B sequence variant 2 (human)
Muellerian-inhibiting factor sequence variant V12G (human)
anti-Muellerian hormone sequence variant 1 (human)
Muellerian-inhibiting factor sequence variant L70P (human)
anti-Muellerian hormone sequence variant 2 (human)
Muellerian-inhibiting factor sequence variant G101V (human)
anti-Muellerian hormone sequence variant 3 (human)
Muellerian-inhibiting factor sequence variant R123W (human)
anti-Muellerian hormone sequence variant 4 (human)
Muellerian-inhibiting factor sequence variant Y167C (human)
anti-Muellerian hormone sequence variant 5 (human)
Muellerian-inhibiting factor sequence variant R194C (human)
anti-Muellerian hormone sequence variant 6 (human)
Muellerian-inhibiting factor sequence variant V477A (human)
anti-Muellerian hormone sequence variant 7 (human)
cartilage oligomeric matrix protein sequence variant P276R (human)
cartilage oligomeric matrix protein sequence variant 1 (human)
cartilage oligomeric matrix protein sequence variant C387G (human)
cartilage oligomeric matrix protein sequence variant 10 (human)
cartilage oligomeric matrix protein sequence variant D408Y (human)
cartilage oligomeric matrix protein sequence variant 11 (human)
cartilage oligomeric matrix protein sequence variant D420A (human)
cartilage oligomeric matrix protein sequence variant 12 (human)
cartilage oligomeric matrix protein sequence variant G440E (human)
cartilage oligomeric matrix protein sequence variant 13 (human)
cartilage oligomeric matrix protein sequence variant G440R (human)
cartilage oligomeric matrix protein sequence variant 14 (human)
cartilage oligomeric matrix protein sequence variant N453S (human)
cartilage oligomeric matrix protein sequence variant 15 (human)
cartilage oligomeric matrix protein sequence variant D439V (human)
cartilage oligomeric matrix protein sequence variant 16 (human)
cartilage oligomeric matrix protein sequence variant C468Y (human)
cartilage oligomeric matrix protein sequence variant 17 (human)
cartilage oligomeric matrix protein sequence variant D472Y (human)
cartilage oligomeric matrix protein sequence variant 18 (human)
cartilage oligomeric matrix protein sequence variant D473G (human)
cartilage oligomeric matrix protein sequence variant 19 (human)
cartilage oligomeric matrix protein sequence variant D290N (human)
cartilage oligomeric matrix protein sequence variant 2 (human)
cartilage oligomeric matrix protein sequence variant D482G (human)
cartilage oligomeric matrix protein sequence variant 20 (human)
cartilage oligomeric matrix protein sequence variant D518N (human)
cartilage oligomeric matrix protein sequence variant 21 (human)
cartilage oligomeric matrix protein sequence variant G719D (human)
cartilage oligomeric matrix protein sequence variant 22 (human)
cartilage oligomeric matrix protein sequence variant N523K (human)
cartilage oligomeric matrix protein sequence variant 23 (human)
cartilage oligomeric matrix protein sequence variant T585M (human)
cartilage oligomeric matrix protein sequence variant 24 (human)
cartilage oligomeric matrix protein sequence variant T585R (human)
cartilage oligomeric matrix protein sequence variant 25 (human)
cartilage oligomeric matrix protein sequence variant 26 (human)
cartilage oligomeric matrix protein sequence variant D372del (human)
cartilage oligomeric matrix protein sequence variant 27 (human)
cartilage oligomeric matrix protein sequence variant D374del (human)
cartilage oligomeric matrix protein sequence variant 28 (human)
cartilage oligomeric matrix protein sequence variant S459del (human)
cartilage oligomeric matrix protein sequence variant 29 (human)
cartilage oligomeric matrix protein sequence variant G299R (human)
cartilage oligomeric matrix protein sequence variant 3 (human)
cartilage oligomeric matrix protein sequence variant D469del (human)
cartilage oligomeric matrix protein sequence variant 30 (human)
cartilage oligomeric matrix protein sequence variant D473del (human)
cartilage oligomeric matrix protein sequence variant 31 (human)
cartilage oligomeric matrix protein sequence variant 32 (human)
cartilage oligomeric matrix protein sequence variant 33 (human)
cartilage oligomeric matrix protein sequence variant C328R (human)
cartilage oligomeric matrix protein sequence variant 4 (human)
cartilage oligomeric matrix protein sequence variant D342Y (human)
cartilage oligomeric matrix protein sequence variant 5 (human)
cartilage oligomeric matrix protein sequence variant C348R (human)
cartilage oligomeric matrix protein sequence variant 6 (human)
cartilage oligomeric matrix protein sequence variant D361V (human)
cartilage oligomeric matrix protein sequence variant 7 (human)
cartilage oligomeric matrix protein sequence variant D361Y (human)
cartilage oligomeric matrix protein sequence variant 8 (human)
cartilage oligomeric matrix protein sequence variant C371S (human)
cartilage oligomeric matrix protein sequence variant 9 (human)
CREB-binding protein sequence variant R1378P (human)
CREB-binding protein sequence variant 1 (human)
cartilage-derived morphogenetic protein 1
nodal protein sequence variant R183Q (human)
nodal protein sequence variant 1 (human)
pituitary homeobox 2 sequence variant R89W (human)
pituitary homeobox 2 sequence variant 1 (human)
pituitary homeobox 2 sequence variant L100Q (human)
pituitary homeobox 2 sequence variant 2 (human)
pituitary homeobox 2 sequence variant T114P (human)
pituitary homeobox 2 sequence variant 3 (human)
pituitary homeobox 2 sequence variant R115H (human)
pituitary homeobox 2 sequence variant 4 (human)
pituitary homeobox 2 sequence variant R137P (human)
pituitary homeobox 2 sequence variant 5 (human)
activin receptor type-1-like sequence variant G48R (human)
serine/threonine-protein kinase receptor R3 sequence variant 1 (human)
activin receptor type-1-like sequence variant E215K (human)
serine/threonine-protein kinase receptor R3 sequence variant 10 (human)
activin receptor type-1-like sequence variant H222del (human)
serine/threonine-protein kinase receptor R3 sequence variant 11 (human)
activin receptor type-1-like sequence variant S233del (human)
serine/threonine-protein kinase receptor R3 sequence variant 12 (human)
activin receptor type-1-like sequence variant G223R (human)
serine/threonine-protein kinase receptor R3 sequence variant 13 (human)
activin receptor type-1-like sequence variant K229R (human)
serine/threonine-protein kinase receptor R3 sequence variant 14 (human)
activin receptor type-1-like sequence variant D254del (human)
serine/threonine-protein kinase receptor R3 sequence variant 15 (human)
activin receptor type-1-like sequence variant M376V (human)
serine/threonine-protein kinase receptor R3 sequence variant 16 (human)
activin receptor type-1-like sequence variant L285F (human)
serine/threonine-protein kinase receptor R3 sequence variant 17 (human)
activin receptor type-1-like sequence variant A306P (human)
serine/threonine-protein kinase receptor R3 sequence variant 18 (human)
activin receptor type-1-like sequence variant H314Y (human)
serine/threonine-protein kinase receptor R3 sequence variant 19 (human)
activin receptor type-1-like sequence variant W50C (human)
serine/threonine-protein kinase receptor R3 sequence variant 2 (human)
activin receptor type-1-like sequence variant S333I (human)
serine/threonine-protein kinase receptor R3 sequence variant 20 (human)
activin receptor type-1-like sequence variant L337P (human)
serine/threonine-protein kinase receptor R3 sequence variant 21 (human)
activin receptor type-1-like sequence variant C344Y (human)
serine/threonine-protein kinase receptor R3 sequence variant 22 (human)
activin receptor type-1-like sequence variant A347P (human)
serine/threonine-protein kinase receptor R3 sequence variant 23 (human)
activin receptor type-1-like sequence variant R374Q (human)
serine/threonine-protein kinase receptor R3 sequence variant 24 (human)
activin receptor type-1-like sequence variant R374W (human)
serine/threonine-protein kinase receptor R3 sequence variant 25 (human)
activin receptor type-1-like sequence variant P378L (human)
serine/threonine-protein kinase receptor R3 sequence variant 26 (human)
activin receptor type-1-like sequence variant E379K (human)
serine/threonine-protein kinase receptor R3 sequence variant 27 (human)
activin receptor type-1-like sequence variant M376R (human)
serine/threonine-protein kinase receptor R3 sequence variant 28 (human)
activin receptor type-1-like sequence variant D397G (human)
serine/threonine-protein kinase receptor R3 sequence variant 29 (human)
activin receptor type-1-like sequence variant C51Y (human)
serine/threonine-protein kinase receptor R3 sequence variant 3 (human)
activin receptor type-1-like sequence variant I398N (human)
serine/threonine-protein kinase receptor R3 sequence variant 30 (human)
activin receptor type-1-like sequence variant W399S (human)
serine/threonine-protein kinase receptor R3 sequence variant 31 (human)
activin receptor type-1-like sequence variant E407D (human)
serine/threonine-protein kinase receptor R3 sequence variant 32 (human)
activin receptor type-1-like sequence variant R411P (human)
serine/threonine-protein kinase receptor R3 sequence variant 33 (human)
activin receptor type-1-like sequence variant R411Q (human)
serine/threonine-protein kinase receptor R3 sequence variant 34 (human)
activin receptor type-1-like sequence variant R411W (human)
serine/threonine-protein kinase receptor R3 sequence variant 35 (human)
activin receptor type-1-like sequence variant P424T (human)
serine/threonine-protein kinase receptor R3 sequence variant 36 (human)
activin receptor type-1-like sequence variant F425L (human)
serine/threonine-protein kinase receptor R3 sequence variant 37 (human)
activin receptor type-1-like sequence variant F425V (human)
serine/threonine-protein kinase receptor R3 sequence variant 38 (human)
activin receptor type-1-like sequence variant F425del (human)
serine/threonine-protein kinase receptor R3 sequence variant 39 (human)
activin receptor type-1-like sequence variant R67Q (human)
serine/threonine-protein kinase receptor R3 sequence variant 4 (human)
activin receptor type-1-like sequence variant R479L (human)
serine/threonine-protein kinase receptor R3 sequence variant 40 (human)
activin receptor type-1-like sequence variant A482V (human)
serine/threonine-protein kinase receptor R3 sequence variant 41 (human)
activin receptor type-1-like sequence variant R484W (human)
serine/threonine-protein kinase receptor R3 sequence variant 42 (human)
activin receptor type-1-like sequence variant K487T (human)
serine/threonine-protein kinase receptor R3 sequence variant 43 (human)
activin receptor type-1-like sequence variant GA48/49EP (human)
serine/threonine-protein kinase receptor R3 sequence variant 44 (human)
activin receptor type-1-like sequence variant R67W (human)
serine/threonine-protein kinase receptor R3 sequence variant 5 (human)
activin receptor type-1-like sequence variant C77W (human)
serine/threonine-protein kinase receptor R3 sequence variant 6 (human)
activin receptor type-1-like sequence variant N96D (human)
serine/threonine-protein kinase receptor R3 sequence variant 7 (human)
activin receptor type-1-like sequence variant D179A (human)
serine/threonine-protein kinase receptor R3 sequence variant 8 (human)
activin receptor type-1-like sequence variant G211D (human)
serine/threonine-protein kinase receptor R3 sequence variant 9 (human)
TGF-beta 1 sequence variant L10P (human)
TGF-beta 1 sequence variant T81H (human)
TGF-beta 1 sequence variant R218C (human)
negative regulation of apoptotic process
TGF-beta 1 sequence variant R218H (human)
TGF-beta 1 sequence variant H222D (human)
TGF-beta 1 sequence variant C225R (human)
growth/differentiation factor 5 sequence variant C400Y (human)
growth/differentiation factor 5 sequence variant 1 (human)
growth/differentiation factor 5 sequence variant R438L (human)
growth/differentiation factor 5 sequence variant 2 (human)
growth/differentiation factor 5 sequence variant L441P (human)
growth/differentiation factor 5 sequence variant 3 (human)
fibular hypoplasia and complex brachydactyly
growth/differentiation factor 5 sequence variant 5 (mouse)
TGF-beta 1 sequence variant T81H cleaved 1 (human)
TGF-beta 1 sequence variant 2 cleaved 1 (human)
TGF-beta 1 sequence variant T81H cleaved 2 (human)
TGF-beta 1 sequence variant 2 cleaved 2 (human)
TGF-beta 1 sequence variant R218C cleaved 1 (human)
TGF-beta 1 sequence variant 3 cleaved 1 (human)
TGF-beta 1 sequence variant R218C cleaved 2 (human)
TGF-beta 1 sequence variant 3 cleaved 2 (human)
TGF-beta 1 sequence variant H222D cleaved 1 (human)
TGF-beta 1 sequence variant 5 cleaved 1 (human)
TGF-beta 1 sequence variant H222D cleaved 2 (human)
TGF-beta 1 sequence variant 5 cleaved 2 (human)
TGF-beta 1 sequence variant C225R cleaved 1 (human)
TGF-beta 1 sequence variant 6 cleaved 1 (human)
TGF-beta 1 sequence variant C225R cleaved 2 (human)
TGF-beta 1 sequence variant 6 cleaved 2 (human)
TGF-beta 1 sequence variant R218H cleaved 1 (human)
TGF-beta 1 sequence variant 4 cleaved 1 (human)
TGF-beta 1 sequence variant R218H cleaved 2 (human)
TGF-beta 1 sequence variant 4 cleaved 2 (human)
DNA-binding transcription factor activity, RNA polymerase II-specific
voltage-gated potassium channel alpha subunit with PAS domain
voltage-gated potassium channel activity
voltage-gated potassium channel subunit KQT
voltage-gated potassium channel alpha subunit
modulatory voltage-gated potassium channel subunit KCNG
modulatory voltage-gated potassium channel subunit KCNS
voltage-gated potassium channel subunit Kv5.1
delayed rectifier potassium channel activity
neuronal potassium channel alpha subunit HNKA
voltage-gated potassium channel subunit Kv8.1
voltage-gated potassium channel subunit Kv8.2
cyclic nucleotide-gated channel alpha-1 sequence variant S320F (human)
cGMP-gated cation channel alpha-1 sequence variant 1 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant R283Q (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 1 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant T291R (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 2 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant G557R (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 3 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant V529M (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 4 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant R283W (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 5 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant F547L (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 6 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant R410W (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 7 (human)
cyclic nucleotide-gated channel alpha-3 sequence variant P163L (human)
cyclic nucleotide-gated cation channel alpha-3 sequence variant 8 (human)
cyclic nucleotide-gated channel beta-3 sequence variant S435F (human)
cyclic nucleotide-gated cation channel beta-3 sequence variant 1 (human)
UniProtKB:Q9NQW8-1, Ser-435, CHEBI:29997
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant D553N (human)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 1 (human)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant S672R (human)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 2 (human)
intracellularly cAMP-activated cation channel activity
voltage-gated monoatomic cation channel activity
voltage-gated potassium channel KCNV2 sequence variant G459D (human)
voltage-gated potassium channel KCNV2 sequence variant 1 (human)
voltage-gated potassium channel KCNV2 sequence variant A259V (human)
voltage-gated potassium channel KCNV2 sequence variant 2 (human)
voltage-gated potassium channel KCNV2 sequence variant L126Q (human)
voltage-gated potassium channel KCNV2 sequence variant 3 (human)
voltage-gated potassium channel KCNV2 sequence variant 4 (human)
voltage-gated potassium channel KCNV2 sequence variant S256W (human)
voltage-gated potassium channel KCNV2 sequence variant 5 (human)
voltage-gated potassium channel KCNV2 sequence variant W188C (human)
voltage-gated potassium channel KCNV2 sequence variant 6 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant T587M (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 1 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant S373P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 10 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R243C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 11 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant D317N (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 12 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant V310I (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 13 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant S566F (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 14 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant Y315C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 15 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant S225L (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 16 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A178P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 17 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A178T (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 18 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G189R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 19 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant P448R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 2 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant T309R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 20 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R591H (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 21 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R366W (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 22 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant I313M (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 23 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant Y111C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 24 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R533W (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 25 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G168R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 26 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant E261D (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 27 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A371T (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 28 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 29 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A341V (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 3 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant L250H (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 30 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant S349W (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 31 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant T391I (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 32 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant K318N (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 33 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A344V (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 34 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A525T (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 35 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A341E (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 36 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R583C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 37 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant D242N (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 38 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant L342F (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 39 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G306R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 4 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant S140G (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 40 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G269S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 41 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R555C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 42 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R539W (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 43 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant Y315S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 44 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R174H (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 45 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A194P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 46 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant Y184S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 47 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G345E (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 48 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R190Q (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 49 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant T311I (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 5 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G314S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 50 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant W248R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 51 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R366P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 52 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R366Q (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 53 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant E160K (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 54 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant V254M (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 55 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G345R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 56 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant E261K (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 57 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant V307L (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 58 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant F339del (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 59 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R243H (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 6 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G179S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 60 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant A300T (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 61 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R174C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 62 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant W305S (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 63 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant L266P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 64 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant R594Q (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 65 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant L273F (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 66 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant Y281C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 67 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant P320A (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 68 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant F157C (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 69 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant L353P (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 7 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G325R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 70 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant W392R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 71 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G269D (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 72 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G589D (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 73 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant G216R (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 74 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant V417M (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 8 (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant T312I (human)
voltage-gated potassium channel subunit KCNQ1 sequence variant 9 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant S247W (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 1 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant H228Q (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 10 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant R207W (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 2 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant L243F (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 3 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 4 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant Y284C (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 5 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant A306T (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 6 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant R333Q (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 7 (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant M208V (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 8 (human)
voltage-gated potassium channel subunit KCNQ2 isoform 3 sequence variant K526N (human)
voltage-gated potassium channel subunit KCNQ2 sequence variant 9 (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant G285C (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 1 (human)
autosomal dominant nonsyndromic deafness
voltage-gated potassium channel subunit KCNQ4 sequence variant L274H (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 2 (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant G285S (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 3 (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant L281S (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 4 (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant W276S (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 5 (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant G321S (human)
voltage-gated potassium channel subunit KCNQ4 sequence variant 6 (human)
calcium-independent alpha-latrotoxin receptor
G protein-coupled receptor signaling pathway
angiopoietin-1 receptor sequence variant R849W (human)
angiopoietin-1 receptor sequence variant 1 (human)
multiple cutaneous and mucosal venous malformations
Note=Binding to SH2 domain (PF00017) of p85
angiopoietin-1 receptor sequence variant Y897S (human)
angiopoietin-1 receptor sequence variant 2 (human)
voltage-gated potassium channel subunit KCNA5 isoform 2 unmodified form
nucleolar transcription factor 1 isoform UBF2
nucleolar transcription factor 1 isoform 2
nucleolar transcription factor 1 isoform short
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
revised 2022-07-14 by PRO:DAN since original activity GO:0042766 'nucleosome mobilization' was made obsolete.
amyloid-beta precursor protein sequence variant D678N (human)
amyloid-beta precursor protein sequence variant A692G (human)
amyloid-beta precursor protein sequence variant E693G (human)
amyloid-beta precursor protein sequence variant E693K (human)
amyloid-beta precursor protein sequence variant E693Q (human)
amyloid-beta precursor protein sequence variant D694N (human)
amyloid-beta precursor protein sequence variant L705V (human)
amyloid-beta precursor protein sequence variant A713T (human)
amyloid-beta precursor protein sequence variant T714A (human)
amyloid-beta precursor protein sequence variant T714I (human)
amyloid-beta precursor protein sequence variant V715M (human)
amyloid-beta precursor protein sequence variant I716V (human)
amyloid-beta precursor protein sequence variant V717F (human)
amyloid-beta precursor protein sequence variant V717G (human)
amyloid-beta precursor protein sequence variant V717I (human)
amyloid-beta precursor protein sequence variant V717L (human)
amyloid-beta precursor protein sequence variant L723P (human)
amyloid-beta precursor protein sequence variant A673T (human)
amyloid-beta precursor protein sequence variant V715A (human)
amyloid-beta precursor protein sequence variant I716F (human)
amyloid-beta precursor protein sequence variant I716T (human)
amyloid-beta precursor protein sequence variant T719P (human)
amyloid-beta precursor protein sequence variant K724N (human)
amyloid-beta precursor protein sequence variant E682K (human)
amyloid-beta precursor protein sequence variant KM670/671NL (human)
amyloid-beta precursor protein sequence variant E693del (human)
mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 (human)
G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)
platelet endothelial aggregation receptor 1 isoform 1 phosphorylated 1 (human)
E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 (human)
UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048
positive regulation of neuron apoptotic process
positive regulation of stress-activated protein kinase signaling cascade
alpha-actinin-1 isoform 1 phosphorylated 1 (human)
B-cell lymphoma/leukemia 10 isoform 1 phosphorylated 1 (human)
heat shock factor protein 1 isoform Long phosphorylated 1 (human)
transcription cis-regulatory region binding
heat shock factor protein 1 isoform Long phosphorylated 2 (human)
Bcl-2-like protein 11 isoform 1 phosphorylated 1 (human)
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
MyD88-independent toll-like receptor signaling pathway
cytoplasmic pattern recognition receptor signaling pathway
lipopolysaccharide receptor complex 3 (human)
CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human)
CD3 gamma with phosphorylated ITAM (human)
CD3 epsilon:CD3 gamma with phosphorylated ITAM (human)
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
Target=lipooligosaccharide (CHEBI:35371).
T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 (human)
eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human)
eukaryotic translation initiation factor 3 complex
positive regulation of apoptotic process
tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse)
Note=SH2 domain (PF00017) of p85is involved in binding
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)
regulation of DNA damage response, signal transduction by p53 class mediator
glutaminase 1 tetramer (Escherichia coli K-12)
glutaminase 1 tetramer (Bacillus subtilis subsp. subtilis str. 168)
siroheme synthase cysG phosphorylated 1 (Salmonella typhimurium)
Note=Strain information inferred from PDB sequence [PRO:DAN]
siroheme synthase cysG unmodified form (Salmonella typhimurium)
transcription factor Jun isoform 1 phosphorylated 1 (mouse)
phosphocarrier protein HPr isoform 1 phosphorylated 1 (Escherichia coli K-12)
phosphocarrier protein HPr isoform 1 P-Ser-HPr (Escherichia coli K-12)
histidine phosphotransfer kinase activity
phosphoenolpyruvate-dependent sugar phosphotransferase system
regulation of carbohydrate metabolic process
phosphocarrier protein HPr isoform 1 phosphorylated 1 (Bacillus subtilis subsp. subtilis str. 168)
protein max isoform short acetylated 1 (human)
TGF-beta 1 isoform 1 mature form (human)
TGF-beta 1 isoform 1 mature form (mouse)
TGF-beta 1 isoform 1 mature form (green monkey)
smad2 isoform Long phosphorylated 1 (human)
smad2 isoform Long phosphorylated 2 (human)
smad2 isoform Long phosphorylated 3 (human)
smad2 isoform Long phosphorylated 4 (human)
smad2 isoform Short phosphorylated 1 (human)
smad2 isoform Long phosphorylated 1 (mouse)
smad2 isoform Short phosphorylated 1 (mouse)
positive regulation of transforming growth factor beta receptor signaling pathway
smad2-smad4-ski protein complex 1 (human)
Note=Conflicting information with data for complex 2
smad2-smad4-ski protein complex 2 (human)
Note=Conflicting information with data for complex 1
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
transforming growth factor beta receptor complex assembly
ccap-HPr-Ser46-P-cre operator complex (Priestia megaterium)
carbon catabolite repression of transcription
ccap-HPr-Ser46-P-cre operator complex (Bacillus subtilis subsp. subtilis str. 168)
Max-binding protein MNT isoform 1 phosphorylated 1 (human)
Max-binding protein MNT isoform 1 phosphorylated 1 (mouse)
DNA-binding transcription factor binding
c-myc protein isoform 1 acetylated 1 (human)
Evidence=Fig6. Evidence for max short isoform comes from cited sources PMID:15003254, PMID:9162900.
Evidence=Fig6. Evidence for max short isoform comes from cited source PMID:9162900.
Evidence for max short isoform comes from cited source PMID:9162900.
c-myc protein isoform 1 O-glycosylated 1 (human)
regulation of transcription by RNA polymerase II
c-myc protein isoform 1 phosphorylated 1 (mouse)
c-myc protein isoform 1 phosphorylated 2 (mouse)
c-myc protein isoform 1 phosphorylated 2 (human)
c-myc protein isoform 1 phosphorylated 3 (human)
methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human)
3-methylcrotonyl-CoA carboxylase deficiency
methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human)
methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA R385S (human)
methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human)
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB S173L (human)
UniProtKB:Q9HCC0-1, Ser-173, CHEBI:30006
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB E99Q (human)
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB V339M (human)
UniProtKB:Q9HCC0-1, Val-339, CHEBI:16044
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB I437V (human)
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant D172fs (human)
methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB IVS3+5G->T (human)
bacterial-type serine palmitoyltransferase complex (Sphingomonas paucimobilis)
bacterial-type serine palmitoyltransferase complex (Rhizorhabdus wittichii RW1)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse)
Note=GST-BAD is mouse: Cell signaling #9294 pEBG-MBad DNA. Fig8
Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human)
serine palmitoyltransferase complex core 1 (human)
3-oxosphinganine synthetase, acyl-CoA:serine C-2 acyltransferase decarboxylating (human)
serine palmitoyltransferase complex 5 (human)
Evidence=Fig6. Evidence=Fig7. Strong preference for C16-CoA substrate.
serine palmitoyltransferase complex 6 (human)
Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse)
Note=Binding between proteins from heterogeneous species
bacterial-type serine palmitoyltransferase complex (Sphingobacterium multivorum)
mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (human)
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse)
smad3 isoform 1 phosphorylated 1 (human)
smad1 isoform 1 phosphorylated 1 (human)
TGF-beta 1 isoform 1 inactive form (human)
bone morphogenetic protein 2 isoform 1, mature form (human)
thrombospondin-4 isoform 1, signal peptide removed form (human)
substrate-dependent cell migration, cell extension
thrombospondin-1 isoform 1, signal peptide removed form (human)
Rho-associated protein kinase 1 isoform 1 cleaved 1 (human)
mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human)
unique cartilage matrix-associated protein isoform 1
inhibitor of KappaB kinase (IKK) complex (human)
transcription factor PML isoform 1 phosphorylated 1 (human)
Note=This phosphoform is not involved in cell proliferation (GO:0008283).
mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human)
smad1 isoform 1 phosphorylated 1 (mouse)
BH3-interacting domain death agonist isoform 1 cleaved 1 (mouse)
release of cytochrome c from mitochondria
E3 ubiquitin-protein ligase COP1 phosphorylated 1 (human)
Note=Binding between proteins from heterogeneous species. Species information from cited reference PMID:10767298
dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form (human)
E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated 1 (human)
double-stranded RNA-activated factor 1 complex (human)
G1/S-specific cyclin-D1 phosphorylated 1 (human)
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
MYD88s:TIRAP:activated TLR4 receptor (mouse)
MYD88s:Mal:activated TLR4 receptor (mouse)
negative regulation of MyD88-dependent toll-like receptor signaling pathway
IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
ticam1:ticam2:activated TLR4 complex (mouse)
ticam1:ticam2:activated TLR4 complex (human)
Toll-like receptor 1-Toll-like receptor 2 protein complex (human)
apoptosis regulator Bcl-2 isoform 1 phosphorylated 2 (human)
Note=In context of glucocorticoid induced apoptosis
apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human)
Kinase=JNK1 [PR:P45983]. Disrupts Bcl-2 (unmodified)/Beclin 1 complex. Induced in response to ceramide (19029119).
apoptosis regulator Bcl-2 isoform 1 phosphorylated 4 (human)
Kinase=JNK [PR:P45983]. Inducing agent: Cephalostatin 1
apoptosis regulator Bcl-2 isoform 1 phosphorylated 5 (human)
negative regulation of mitotic nuclear division
Kinase=CDC2 [PR:P06493]. Induced by okadaic acid.
beclin-1 isoform 1 phosphorylated 1 (human)
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
Note=Autophosphorylation sites are situated in characteristic Akt substrate motif (RXRXX(S/T)
epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human)
Kinase=Src [PR:P12931; PR:000027234]. Authors did not consider the signal peptide of EGFR (residue 1-24) hence paper refers to Y845 (instead of Y869). Inducing agent: Ionizing radiation.Activates DNA-PK by inducing phosphorylation at T2609
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
interleukin-1-mediated signaling pathway
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
Note=Dissociation from ILR complex. Phosphorylated in PTS domain.
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
pIRAK1:IRAK4:MyD88:Mal:activated TLR4 (human)
nuclear receptor coactivator 3 isoform 1 phosphorylated 1 (human)
nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human)
nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human)
Kinase=c-Abl tyrosine kinase [PR:P00519]. Induced by insulin-like growth factor 1, epidermal growth factor, or estrogen treatment in breast cancer cells
estrogen receptor isoform 1 phosphorylated 1 (human)
positive regulation of DNA-templated transcription
Kinase=IKKepsilon [PR:Q14164; PR:000001778]
estrogen receptor isoform 1 phosphorylated 2 (human)
Kinase=c-Abl tyrosine kinase [PR:P00519; PR:000003582]. interaction mediated by two PXXP motifs of ERalpha and the c-Abl SH3 domain
estrogen receptor isoform 1 acetylated 1 (human)
cellular tumor antigen p53 isoform 1 dimethylated 1 (human)
cellular tumor antigen p53 isoform 1 acetylated 1 (human)
estrogen receptor isoform 1 phosphorylated 4 (human)
cellular tumor antigen p53 isoform 1 methylated 3 (human)
cellular tumor antigen p53 isoform 1 methylated 4 (human)
Lysine methyltransferase, SMYD2 [PR:Q9NRG4].
cellular tumor antigen p53 isoform 1 acetylated 2 (human)
Acetylace=Acetyltransferase EP300 [PR:Q09472; PR:000007102].
cellular tumor antigen p53 isoform 1 phosphorylated 12 (human)
Kinase=NUAK1 [PR:O60285; PR:000011473]. NUAK1 gets activated upon phosphorylation by LKB1.
zinc finger protein ZFPM1 isoform 2 (mouse)
cellular tumor antigen p53 isoform 1 phosphorylated 9 (human)
cellular tumor antigen p53 isoform 1 phosphorylated 11 (human)
nuclear receptor coactivator 3 isoform 1 acetylated 1 (human)
signal transducer and activator of transcription 1 isoform 1 phosphorylated 3 (human)
forkhead box protein O1 isoform 1 phosphorylated 1 (human)
myocyte-specific enhancer factor 2C isoform 2 acetylated 1 (mouse)
cyclin-dependent protein kinase activity
serine/threonine-protein kinase CDG1 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
UniProtKB:Q9LSE1-1, Ser-44/Ser-47/Ser-234, MOD:00046
positive regulation of brassinosteroid mediated signaling pathway
serine/threonine-protein phosphatase BSU1 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
protein serine/threonine/tyrosine kinase activity
brassinosteroid mediated signaling pathway
protein BRASSINAZOLE-RESISTANT 1 phosphorylated 1 (Arabidopsis thaliana)
protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
thrombospondin-1, signal peptide removed form (human)
SCF(TIR1) complex (Arabidopsis thaliana)
auxin-IAA7-SCF(TIR1) complex (Arabidopsis thaliana)
SCF(COI1) complex (Arabidopsis thaliana)
jasmonic acid mediated signaling pathway
serine/threonine-protein kinase BIK1 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
pattern recognition receptor signaling pathway
FLS2:BAK1 complex (Arabidopsis thaliana)
BRI1:BAK1 complex (Arabidopsis thaliana)
zona pellucida receptor complex 1 (mouse)
Note=Purified zona pellucida receptor binding complex shown to bind to solubilized zona pellucida proteins
C-terminal-binding protein 2 isoform 1 acetylated 1 (human)
ETS translocation variant 1 isoform 1 acetylated 1 (human)
endonuclease 8-like 2 isoform 1, initiator methionine removed acetylated 1 (human)
N-glycosylase/DNA lyase isoform 1 acetylated 1 (human)
human 8-oxoguanine-DNA glycosylase acetylated
DNA polymerase beta acetylated 1 (human)
transcription factor Jun isoform 1 acetylated 1 (human)
traf6:ticam1:ticam2:activated TLR4 complex (human)
traf6:trif:tram:activated TLR4 complex (human)
traf3:ticam1:ticam2:activated TLR4 complex (mouse)
microtubule-associated protein tau sequence variant R5H (human)
microtubule-associated protein tau sequence variant R5L (human)
microtubule-associated protein tau sequence variant N296del (human)
SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 myristoylated 1 (mouse)
1-aminocyclopropane-1-carboxylate synthase 6 phosphorylated 1 (Arabidopsis thaliana)
UniProtKB:Q9SAR0, Ser-480/Ser-483/Ser-488, MOD:00046
Kinase=MPK6 [PR:Q39026]. Phosphorylation promotes protein stability [PMID:18182027]
positive regulation of ethylene biosynthetic process
1-aminocyclopropane-1-carboxylate synthase 2 phosphorylated 1 (Arabidopsis thaliana)
Kinase=MPK6 [PR:Q39026]. Phosphorylation promotes protein stability.
mitogen-activated protein kinase 6 phosphorylated 1 (Arabidopsis thaliana)
Target=PR:P11035. Evidence=ECO:0000181.
histone acetyltransferase KAT2A isoform 1
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human)
Note=Species information in Materials and methods
positive regulation of NF-kappaB transcription factor activity
myogenic factor 6 isoform 1 phosphorylated 1 (rat)
histone deacetylase 4 isoform 1 phosphorylated 1 (human)
histone deacetylase 5 isoform 1 phosphorylated 1 (human)
UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046
myocyte-specific enhancer factor 2A isoform 1 phosphorylated 1 (human)
RNA-binding transcription regulator activity
epidermal growth factor receptor signaling pathway
myocyte-specific enhancer factor 2D isoform 2 phosphorylated 1 (mouse)
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat)
histone H1.5, initiator methionine removed phosphorylated 1 (human)
myoblast determination protein 1 phosphorylated 1 (mouse)
core promoter sequence-specific DNA binding
mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 1 (frog)
Timing=Meiosis I (prophase I, metaphase I, anaphase I, telophase I), Meiosis II (prophase II, metaphase II).
small conductance calcium-activated potassium channel protein 3 sequence variant 1 (human)
calcium-activated potassium channel activity
Note=Sequence not deposited in any database
catenin beta-1 isoform 1 phosphorylated 1 (human)
Note=Phosphorylation at Ser-663 found in human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation.
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (human)
cell division cycle protein 20 homolog unphosphorylated form (human)
cell division cycle protein 20 homolog phosphorylated 1 (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human)
negative regulation of protein phosphorylation
negative regulation of centrosome duplication
GerQ cross-linked complex (Bacillus subtilis subsp. subtilis str. 168)
protein BRASSINAZOLE-RESISTANT 2 phosphorylated 1 (Arabidopsis thaliana)
mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog)
UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047
mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 4 (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 (Schizosaccharomyces pombe 972h-)
mitotic spindle assembly checkpoint signaling
mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-)
mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human)
Timing=Mitosis and spindle disruption (nocodazole).
mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 1 (yeast)
mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 10 (human)
serine-protein kinase ATM phosphorylated 2 (human)
condensed chromosome, centromeric region
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog)
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human)
attachment of spindle microtubules to kinetochore
mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form (frog)
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human)
Timing=prophase, prometaphase, metaphase.
mitotic checkpoint protein BUB3 phosphorylated 1 (human)
cell division cycle protein 20 homolog phosphorylated 3 (human)
cell division cycle protein 20 homolog phosphorylated 4 (frog)
cellular tumor antigen p53 isoform 1 phosphorylated 1 (human)
Note=HIV-1-Env-induced syncytium formation leads to apoptosis via a pathway that involves p53S15 phosphorylation by mTOR/FRAP.
cell division cycle protein 27 phosphorylated 1 (human)
T-complex protein 1 subunit epsilon isoform 1 phosphorylated 1 (mouse)
T-complex protein 1 subunit eta isoform 1 phosphorylated 1 (mouse)
breast cancer type 2 susceptibility protein phosphorylated 1 (human)
spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast)
negative regulation of endopeptidase activity
serine/threonine-protein kinase haspin phosphorylated 1 (human)
histone H3, initiator methionine removed phosphorylated 1 (human)
protein localization to chromosome, centromeric region
Target=PR:Q96GD4. Target=PR:Q9NQS7. Target=PR:O15392. Target=PR:Q53HL2.
inner centromere protein phosphorylated 1 (human)
outer kinetochore KNL1 complex subunit SPC105 phosphorylated 1 (yeast)
segment polarity protein dishevelled homolog DVL-2 phosphorylated 1 (human)
segment polarity protein dishevelled homolog DVL-2 unphosphorylated form (human)
outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)
disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
glutamate receptor-interacting protein 1 isoform 2 palmitoylated 1 (mouse)
cystin-1 isoform 1, N-terminal myristoylated form (mouse)
disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
aurora kinase B unphosphorylated form (human)
aurora kinase B phosphorylated 1 (human)
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse)
UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115
serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse)
lipopolysaccharide-binding protein, signal peptide removed form (human)
CD14 molecule cleaved 2 GPI-anchored form (human)
CD14 molecule cleaved 2 soluble form (human)
Note=Expressed in supernatant of microglial cells
interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
positive regulation of transcription initiation by RNA polymerase II
interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
traf6:ticam1:ticam2:activated TLR4 complex (mouse)
traf6:trif:tram:activated TLR4 complex (mouse)
TNF receptor-associated factor 6 K63-polyubiquitinated 1 (human)
pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-pUb-TRAF6 (human)
MyD88-dependent toll-like receptor signaling pathway
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human)
free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:TRAF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)
free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human)
K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)
pUb-TRAF6:TAB1:TAB2/TAB3:free polyubiquitin chain : phospho-TAK1 (human)
shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana)
negative regulation of brassinosteroid mediated signaling pathway
receptor-like serine/threonine-protein kinase SD1-7 isoform 1 phosphorylated 1 (Arabidopsis thaliana)
catenin beta-1 isoform 1 phosphorylated 2 (human)
catenin beta-1 isoform 1 phosphorylated 3 (human)
catenin beta-1 isoform 1 phosphorylated 4 (human)
serine/threonine-protein kinase PAK 1 phosphorylated 1 (human)
protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 5 (Arabidopsis thaliana)
At protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 4
negative regulation of multicellular organism growth
BRI1 kinase inhibitor 1 phosphorylated 1 (Arabidopsis thaliana)
UniProtKB:Q9FMZ0, Ser-270/Ser-274, MOD:00046
BRI1 kinase inhibitor 1 unphosphorylated form (Arabidopsis thaliana)
activated IkappaB kinase complex (human)
nuclear factor NF-kappa-B p50 subunit (human)
BRI1 kinase inhibitor 1 phosphorylated 2 (Arabidopsis thaliana)
uric acid degradation bifunctional protein TTL phosphorylated 1 (Arabidopsis thaliana)
transcription factor MYBL2(At1g71030) phosphorylated 1 (Arabidopsis thaliana)
chorion-specific transcription factor GCMa acetylated 1 (mouse)
positive regulation of syncytium formation by plasma membrane fusion
shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana)
negative regulation of flower development
negative regulation of developmental growth
protein BRASSINAZOLE-RESISTANT 2 phosphorylated 2 (Arabidopsis thaliana)
BES1/BZR1 homolog protein 2 phosphorylated 1 (Arabidopsis thaliana)
shaggy-related protein kinase theta unphosphorylated form (Arabidopsis thaliana)
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 phosphorylated 1 (Arabidopsis thaliana)
positive regulation of multicellular organism growth
protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 6 (Arabidopsis thaliana)
negative regulation of protein kinase activity
protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana)
positive regulation of flower development
U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana)
negative regulation of defense response to bacterium
mitogen-activated protein kinase kinase 4 phosphorylated 1 (Arabidopsis thaliana)
regulation of stomatal complex patterning
shaggy-related protein kinase eta unphosphorylated form (Arabidopsis thaliana)
serine/threonine-protein kinase BSK1 phosphorylated 1 (Arabidopsis thaliana)
Note=phosphorylation experiment in vitro.
protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 7 (Arabidopsis thaliana)
U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana)
peptidyl-prolyl cis-trans isomerase CYP18-3 unphosphorylated form (Arabidopsis thaliana)
auxin response factor 2 phosphorylated 1 (Arabidopsis thaliana)
protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 8 (Arabidopsis thaliana)
traf3:ticam1:ticam2:activated TLR4 complex (human)
rip1:ticam1:ticam2:activated TLR4 complex (human)
RIP1:trif:tram:activated TLR4 complex (human)
sarm:ticam1:ticam2:activated TLR4 complex (human)
negative regulation of MyD88-independent toll-like receptor signaling pathway
IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF3 (human)
IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF7 (human)
IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF3 (human)
IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF7 (human)
K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
K63-poly-Ub-TRAF3:TRIF:TRAM:activated TLR4 (human)
K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-pUb-RIP1 (human)
receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 (human)
IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:K63-pUb-RIP1:IKKcomplex (human)
rip3:ticam1:ticam2:activated TLR4 complex (human)
rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human)
rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
rip1:traf6:trif:tram:activated TLR4 complex (mouse)
p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human)
p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-IKK epsilon (human)
TIRAP:PIP2:activated TLR4 complex (human)
lipopolysaccharide receptor complex 3; plasma membrane (human)
TLR4:MD2:LPS:CD14 [plasma membrane] (human)
lipopolysaccharide receptor complex 3; endosome membrane (human)
TLR4:MD2:LPS:CD14 [endosome membrane] (human)
doublesex- and mab-3-related transcription factor 1 homodimer (mouse)
doublesex and mab-3 related transcription factor 2 homodimer (mouse)
doublesex- and mab-3-related transcription factor A1 homodimer (mouse)
doublesex- and mab-3-related transcription factor A2 homodimer (mouse)
doublesex- and mab-3-related transcription factor C2 homodimer (mouse)
negative regulation of DNA-binding transcription factor activity
interleukin-15 receptor subunit alpha isoform 1
interferon gamma isoform 1, signal peptide removed glycosylated form (mouse)
Note=Mature IFGN is heterogeneous in its C-terminus
TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)
TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)
Note=The binding is shown to the ectodomain. The form is inferred by curator.
chordin isoform 1, signal peptide removed form (mouse)
chordin isoform 1, signal peptide removed form (frog)
follistatin isoform 1, signal peptide removed glycosylated form (human)
follistatin isoform 1 cleaved and N-glycosylated 2 (pig)
follistatin isoform 1 cleaved and N-glycosylated 2 (human)
follistatin isoform 2, signal peptide removed N-glycosylated 1 (human)
growth/differentiation factor 5 sequence variant V186* (mouse)
interferon gamma isoform 1, signal peptide removed form (mouse)
Note=Recombinant mature protein not glycosylated
interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human)
Note=Glycosylation sites by similarity but shown to be glycoprotein [PMIDs:10823661, 2434486]
interferon gamma isoform 1 cleaved and N-glycosylated 2 (human)
noggin isoform 1, signal peptide removed form (human)
BMP receptor type-1A isoform 1 phosphorylated 1 (human)
BMP receptor type-1A isoform 1 phosphorylated 1 (mouse)
BMP receptor type-1B isoform 1 phosphorylated 1 (mouse)
BMP receptor type-1B isoform 1 phosphorylated 1 (human)
positive regulation of cell differentiation
DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (human)
DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (rat)
DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human)
DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse)
RING-box protein 2 isoform 1 phosphorylated 1 (human)
TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
activin receptor type-1B isoform 1 phosphorylated 1 (human)
activin receptor type-1C isoform 1 phosphorylated 1 (human)
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse)
anterior/posterior pattern specification
activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human)
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse)
activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)
regulation of activin receptor signaling pathway
activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human)
activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)
Muellerian-inhibiting factor isoform 1 mature N-glycosylated 2 (human)
c-myc protein isoform 1 phosphorylated 1 (human)
cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human)
CREB-binding protein isoform 1 methylated 1 (mouse)
epidermal growth factor receptor binding
decorin isoform A cleaved and glycosylated 1 (human)
tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human)
tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human)
latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (human)
latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (mouse)
latent TGF-beta-binding protein 1 isoform 1, signal peptide removed form (human)
transforming growth factor beta receptor activity
mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse)
mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (rat)
mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (mouse)
nodal protein isoform 1, signal peptide removed form (mouse)
Note=Sequence coordinates of mature not determined
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
Note=hyperphosphorylated by CdKs, phosphorylated residue important for proteasome targeting Ser-672.
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse)
Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
signal transduction in response to DNA damage
ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human)
ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human)
mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
thrombospondin-1 isoform 1 cleaved 2 (mouse)
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
thrombospondin-2 isoform 1, signal peptide removed form (human)
thrombospondin-3 isoform 1, signal peptide removed form (mouse)
transcription factor Sp1 isoform 1 acetylated 1 (human)
transcription factor Sp1 isoform 1 cleaved 1 (human)
transcription factor Sp1 isoform 1 O-glycosylated 1 (human)
transcription factor Sp1 isoform 1 phosphorylated 1 (human)
transcription factor Sp1 isoform 1 phosphorylated 2 (human)
transcription factor Sp1 isoform 1 phosphorylated 3 (human)
transcription factor Sp1 isoform 1 phosphorylated 4 (human)
transcription factor Sp1 isoform 1 sumoylated 1 (human)
tumor necrosis factor isoform 1 cleaved 1 (human)
tumor necrosis factor isoform 1 cleaved 1 (mouse)
tumor necrosis factor isoform 1 cleaved 2 (mouse)
tumor necrosis factor isoform 1 myristoylated 1 (human)
tumor necrosis factor isoform 1 phosphorylated 1 (human)
bone morphogenetic protein 2 isoform 1, mature form (mouse)
bone morphogenetic protein 4 isoform 1, mature form (human)
positive regulation of protein phosphorylation
bone morphogenetic protein 4 isoform 1, mature form (mouse)
bone morphogenetic protein 5 isoform 1, mature form (human)
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)
Note=The active protein region comes from crystal structure.
positive regulation of aldosterone biosynthetic process
bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)
bone morphogenetic protein 7 isoform 1, mature form (mouse)
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
positive regulation of canonical NF-kappaB signal transduction
positive regulation of non-canonical NF-kappaB signal transduction
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (cow)
TGF-beta 1 isoform 1 latency associated peptide (human)
TGF-beta 1 isoform 1 inactive form (green monkey)
TGF-beta 1 isoform 1 inactive form (mouse)
activin/inhibin beta A chain isoform 1 mature form (mouse)
activin/inhibin beta A chain isoform 1 mature form (human)
activin/inhibin beta B chain isoform 1 mature form (human)
regulation of follicle-stimulating hormone secretion
activin/inhibin beta E chain isoform 1 mature form (mouse)
growth/differentiation factor 5 isoform 1 mature form (human)
growth/differentiation factor 7 isoform 1 mature form (mouse)
inhibin beta C chain isoform 1 mature form (human)
positive regulation of MAP kinase activity
smad1 isoform 1 phosphorylated and ubiquitinated 1 (human)
smad2 isoform Long acetylated and phosphorylated 1 (human)
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
smad2 isoform Short acetylated and phosphorylated 1 (human)
smad3 isoform 1 acetylated and phosphorylated 1 (human)
smad3 isoform 1 phosphorylated 1 (mouse)
UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046
smad3 isoform 1 phosphorylated 2 (mouse)
UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047
smad3 isoform 1 phosphorylated 3 (mouse)
smad5 isoform 1 phosphorylated 1 (human)
smad5 isoform 1 phosphorylated 1 (mouse)
transcription regulator inhibitor activity
smad9 isoform 1 phosphorylated 1 (mouse)
UniProtKB:Q9JIW5-1, Ser-428/Ser-430, MOD:00046
potassium voltage-gated channel subfamily A member 5 isoform 1 sequence variant E375* (human)
cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 (cow)
platelet-derived growth factor C isoform 1 cleaved 1 (human)
platelet-derived growth factor C isoform 1 cleaved 1 (mouse)
platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form (human)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 N-glycosylated 1 (mouse)
voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)
voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1 (rat)
voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)
A-type (transient outward) potassium channel activity
A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)
A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)
A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A N-glycosylated 1 (human)
voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A N-glycosylated 1 (mouse)
voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A phosphorylated 1 (human)
voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human)
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
ezrin isoform 1 phosphorylated 2 (human)
ezrin isoform 1 phosphorylated 3 (human)
ezrin isoform 1 phosphorylated 5 (human)
regulation of release of sequestered calcium ion into cytosol
intracellularly ATP-gated chloride channel activity
CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human)
interleukin-1 alpha isoform 1 mature form (human)
interleukin-1 alpha isoform 1 myristoylated 1 (human)
interleukin-1 alpha isoform 1 myristoylated 2 (human)
interleukin-1 alpha isoform 1 phosphorylated 1 (mouse)
interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human)
interleukin-1 type I receptor antagonist activity
interleukin-17A, signal peptide removed form (human)
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
Muellerian-inhibiting factor isoform 1 mature form (human)
Muellerian-inhibiting factor isoform 1 mature form (rat)
inhibin alpha chain isoform 1 cleaved and N-glycosylated 2 (human)
inhibin alpha chain isoform 1 mature form (human)
CD14 molecule cleaved 1 soluble form (human)
tyrosine-protein kinase Lck isoform 1 phosphorylated 1 (human)
Note=This form is enhanced by HIV gp120.
tyrosine-protein kinase Fyn isoform 1 phosphorylated 1 (human)
Note=HIV gp120 inhibits TCR-CD3 mediated phosphorylation of fyn.
moesin isoform 1 phosphorylated 1 (human)
tyrosine-protein kinase Lck isoform 1 phosphorylated 2 (human)
cellular tumor antigen p53 isoform 1 phosphorylated 2 (human)
Note=This form is induced by HIV gp120/gp41.
ezrin isoform 1 phosphorylated 6 (human)
kinesin-like protein KIF11 isoform 1 phosphorylated 1 (human)
initial mitotic spindle pole body separation
transmembrane protease serine 9 isoform 3 cleaved 1 (mouse)
T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human)
Note=Phosphorylated on Tyr residues of its Reth motifs. Phosphorylated by fyn and lck which are mediated by TCR-CD3 which is inhibited by HIV gp120.
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)
Note=This form is induced by HIV gp160 and CD4 ligation.
CD4 molecule isoform 1 phosphorylated 1 (human)
neuropilin-1 isoform 1, signal peptide removed O-glycosylated 1 (human)
vascular endothelial growth factor receptor 2 binding
regulation of vascular endothelial growth factor receptor signaling pathway
neuropilin-1 isoform 1, signal peptide removed O-glycosylated 2 (human)
apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse)
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
neuropilin-1 isoform 1, signal peptide removed form (human)
vascular endothelial growth factor B isoform 1 cleaved 1 (mouse)
mitogen-activated protein kinase 14 phosphorylated 1 (human)
nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 (human)
voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)
outward rectifier potassium channel activity
Bcl-2-like protein 11 isoform 2 phosphorylated 1 (human)
focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)
Note=This form is induced by HIV gp120 exposure.
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse)
PC4 and SFRS1-interacting protein p38 (human)
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (human)
cholera enterotoxin subunit A1 (Vibrio cholerae O1 biovar El Tor str. N16961)
modulation of process of another organism
cholera enterotoxin subunit A2 (Vibrio cholerae O1 biovar El Tor str. N16961)
receptor-interacting serine/threonine-protein kinase 1 isoform 1 ubiquitinated 1 (human)
aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 1 (Escherichia coli K-12)
signal transduction histidine-protein kinase BaeS isoform 1 phosphorylated 1 (Escherichia coli K-12)
transferase activity, transferring phosphorus-containing groups
sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12)
chemotaxis protein CheY isoform 1, initiator methionine removed phosphorylated 1 (Escherichia coli K-12)
sensor protein CreC isoform 1 phosphorylated 1 (Escherichia coli K-12)
sensor protein dcuS isoform 1 phosphorylated 1 (Escherichia coli K-12)
chaperonin GroEL isoform 1, initiator methionine removed form (Escherichia coli K-12)
elongation factor G isoform 1, initiator methionine removed form (Escherichia coli K-12)
large ribosomal subunit protein uL10 isoform 1, initiator methionine removed form (Escherichia coli K-12)
small ribosomal subunit protein bS6 isoform 1 (Escherichia coli K-12)
transcriptional regulatory protein DpiA isoform 1 phosphorylated 1 (Escherichia coli K-12)
DpiA-Pasp DNA-binding transcriptional dual regulator
phosphorelay response regulator activity
fructose-bisphosphate aldolase class 2 isoform 1, initiator methionine removed form (Escherichia coli K-12)
sensor kinase dpiB isoform 1 phosphorylated 1 (Escherichia coli K-12)
regulation of response to external stimulus
tyrosine-protein kinase wzc isoform 1 phosphorylated 1 (Escherichia coli K-12)
isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1 (Escherichia coli K-12)
lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12)
nucleoside diphosphate kinase isoform 1, initiator methionine removed form (Escherichia coli K-12)
purine ribonucleotide biosynthetic process
nucleobase-containing small molecule interconversion
aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 3 (Escherichia coli K-12)
transcriptional regulatory protein DcuR isoform 1 phosphorylated 1 (Escherichia coli K-12)
periplasmic protein TorT isoform 1, signal peptide removed form (Escherichia coli K-12)
tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human)
FASLG isoform 1 sequence variant 1 (human)
FASLG isoform FasL sequence variant 1 (human)
tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human)
tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human)
Note=This variant is naturally found in mice, the annotation here is for the equivalent human form.
tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse)
Faslg isoform 1 sequence variant 1 (mouse)
Faslg isoform FasL sequence variant 1 (mouse)
tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (mouse)
tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (mouse)
Note=Likely strain: TSV01 (traced from acknowledgements); no TaxId for that strain
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
catenin beta-1 isoform 1 phosphorylated 5 (human)
serine/threonine-protein kinase STK11 isoform 1 phosphorylated 1 (mouse)
UniProtKB:Q9WTK7-1, Tyr-261/Tyr-365, MOD:00048
smad7 isoform 1 phosphorylated 1 (mouse)
amyloid-beta precursor protein sequence variant I716M (human)
amyloid-beta precursor protein sequence variant M722K (human)
microtubule-associated protein tau sequence variant Q336H (human)
serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2
positive regulation of peptidyl-tyrosine phosphorylation
serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 (mouse)
serine/threonine-protein kinase STK11 isoform 1 unphosphorylated 1 (mouse)
fusion of virus membrane with host plasma membrane
NS1 hexamer, with complex sugar attached
POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 (mouse)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
cell adhesion molecule CEACAM10, cleaved and N-glycosylated form (mouse)
regulation of actin cytoskeleton organization
C-C motif chemokine 27 isoform 1, signal peptide removed form (mouse)
positive regulation of mononuclear cell migration
catenin beta-1 isoform 1 phosphorylated 6 (human)
catenin beta-1 isoform 1 unphosphorylated 2 (human)
catenin beta-1 isoform 1 phosphorylated 7 (human)
catenin beta-1 isoform 1 phosphorylated 8 (human)
catenin beta-1 isoform 1 phosphorylated 9 (human)
chymotrypsin-like elastase family member 2A, mature form (mouse)
cochlin, signal peptide removed form (mouse)
N-terminal fragment glycosylated (mouse)
positive regulation of innate immune response
sonic hedgehog protein N-product dually lipidated 1 (mouse)
paired box protein Pax-6 isoform 3 sumoylated 1 (mouse)
traf3:ticam1:activated TLR3 complex (human)
traf3:ticam1:activated TLR3 complex (mouse)
tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
TLR3TLR3dsRNATriftraf3TBK1tankIKKe (mouse)
K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human)
p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon (human)
p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human)
SARM:ticam1:activated TLR3 complex (human)
rip3:ticam1:activated TLR3 complex (human)
rip1:ticam1:activated TLR3 complex (human)
rip1:rip3:ticam1:activated TLR3 complex (human)
free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)
pUbtraf6:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-pUb-TRAF6 (human)
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human)
traf6:ticam1:activated TLR3 complex (human)
traf6:trif:tram:activated TLR3 complex (human)
IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3 (human)
IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF7 (human)
IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF3 (human)
IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF7 (human)
K63-pUb-rip1:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-pUb-RIP1 (human)
IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:K63-pUb-RIP1:IKKcomplex (human)
fadd:rip1:ticam1:activated TLR3 complex (human)
pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human)
activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 (human)
ethylene-responsive transcription factor 1 phosphorylated 1 (rice)
ethylene-responsive transcription factor 1 unphosphorylated 1 (rice)
ethylene-responsive transcription factor 6 phosphorylated 1 (Arabidopsis thaliana)
UniProtKB:Q8VZ91, Ser-266/Ser-269, MOD:00046
positive regulation of cellular response to oxidative stress
transcription factor MYB41 phosphorylated 1 (Arabidopsis thaliana)
positive regulation of response to salt stress
MAPK kinase substrate protein At1g80180 phosphorylated 1 (Arabidopsis thaliana)
positive regulation of asymmetric cell division
transcription factor SPEECHLESS phosphorylated 1 (Arabidopsis thaliana)
transcription factor SPEECHLESS unphosphorylated 1 (Arabidopsis thaliana)
ethylene-responsive transcription factor 6 unphosphorylated 1 (Arabidopsis thaliana)
MAPK kinase substrate protein At1g80180 unphosphorylated 1 (Arabidopsis thaliana)
mRNA-decapping enzyme-like protein phosphorylated 1 (Arabidopsis thaliana)
positive regulation of response to water deprivation
mRNA-decapping enzyme-like protein unphosphorylated 1 (Arabidopsis thaliana)
nitrate reductase [NADH] 2 phosphorylated 1 (Arabidopsis thaliana)
protein ETHYLENE INSENSITIVE 3 phosphorylated 1 (Arabidopsis thaliana)
negative regulation of ethylene-activated signaling pathway
protein ETHYLENE INSENSITIVE 3 phosphorylated 2 (Arabidopsis thaliana)
CBL-interacting serine/threonine-protein kinase 24 phosphorylated 1 (Arabidopsis thaliana)
CBL-interacting serine/threonine-protein kinase 24 phosphorylated 2 (Arabidopsis thaliana)
CBL-interacting serine/threonine-protein kinase 24 phosphorylated 3 (Arabidopsis thaliana)
calcineurin B-like protein 2 phosphorylated 1 (Arabidopsis thaliana)
calcineurin B-like protein 2 unphosphorylated 1 (Arabidopsis thaliana)
TIRAP:PIP2:BTK:activated TLR4 complex (human)
MAL:PI(4,5)P2:BTK:activated TLR4 (human)
Target=PR:000037447 (TIRAP protein in this complex).
pTIRAP:PIP2:BTK:activated TLR4 complex (human)
p-4Y-MAL:PI(4,5)P2:BTK:activated TLR4 (human)
p-4Y-TIRAP:PI(4,5)P2:BTK:activated TLR4 (human)
LPS:transmembrane CD14 complex (chicken)
positive regulation of nitric oxide biosynthetic process
Evidence=ECO:0000305, PMID:24034933 shows the increase of CD14 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex LPS:CD14 has been inferred by curator based on expression data and conserved TLR signaling response. Note=In response to laryngotracheitis virus.
CD14 molecule cleaved 1 soluble form (mouse)
Evidence=ECO:0000305, PMID:24034933 shows the increase of TLR4 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex with MD2 has been inferred by curator based on PMID:18768894. Note=In response to laryngotracheitis virus.
MYD88:TIRAP:activated TLR4 receptor (chicken)
MYD88:MAL:activated TLR4 receptor (chicken)
MYD88:MAL:LY96:TLR4:LPS complex (chicken)
lipopolysaccharide receptor complex 3 (mouse)
DNA (cytosine-5)-methyltransferase 1 unphosphorylated 1 (human)
DNA (cytosine-5)-methyltransferase 1 phosphorylated 1 (human)
DNA (cytosine-5)-methyltransferase 1 phosphorylated 2 (human)
transcriptional coactivator YAP1 isoform 3 unphosphorylated 1 (human)
Note=A?(25-35) induced YAP translocation from cytoplasm to nucleus accompanied with the increased phosphorylation on Y357, resulting in the enhancement of interaction between YAP and p73.
transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human)
transcriptional coactivator YAP1 phosphorylated 1 (human)
G1/S-specific cyclin-D1 unphosphorylated 1 (human)
catenin beta-1 isoform 1 phosphorylated 11 (human)
amyloid-beta precursor protein sequence variant A673V (human)
amyloid-beta precursor protein sequence variant D678H (human)
amyloid-beta precursor protein sequence variant K687N (human)
microtubule-associated protein tau sequence variant K257T (human)
microtubule-associated protein tau sequence variant L266V (human)
microtubule-associated protein tau sequence variant G272V (human)
microtubule-associated protein tau sequence variant N279K (human)
microtubule-associated protein tau sequence variant K280del (human)
microtubule-associated protein tau sequence variant L284R (human)
microtubule-associated protein tau sequence variant N296H (human)
microtubule-associated protein tau sequence variant P301S (human)
microtubule-associated protein tau sequence variant P301L (human)
microtubule-associated protein tau sequence variant G303V (human)
microtubule-associated protein tau sequence variant S305N (human)
microtubule-associated protein tau sequence variant K317M (human)
microtubule-associated protein tau sequence variant S320Y (human)
microtubule-associated protein tau sequence variant S320F (human)
microtubule-associated protein tau sequence variant V337M (human)
microtubule-associated protein tau sequence variant E342V (human)
microtubule-associated protein tau sequence variant S352L (human)
microtubule-associated protein tau sequence variant K369I (human)
microtubule-associated protein tau sequence variant G389R (human)
microtubule-associated protein tau sequence variant R406W (human)
microtubule-associated protein tau sequence variant N410H (human)
presenilin-1 sequence variant A79V (human)
presenilin-1 sequence variant V82L (human)
presenilin-1 sequence variant L85P (human)
presenilin-1 sequence variant V89L (human)
presenilin-1 sequence variant C92S (human)
presenilin-1 sequence variant V94M (human)
presenilin-1 sequence variant V96F (human)
presenilin-1 sequence variant V97L (human)
presenilin-1 sequence variant F105I (human)
presenilin-1 sequence variant F105V (human)
presenilin-1 sequence variant F105C (human)
presenilin-1 sequence variant F105L (human)
presenilin-1 sequence variant L113Q (human)
presenilin-1 sequence variant Y115H (human)
presenilin-1 sequence variant Y115C (human)
presenilin-1 sequence variant Y115D (human)
presenilin-1 sequence variant T116I (human)
presenilin-1 sequence variant T116N (human)
presenilin-1 sequence variant P117S (human)
presenilin-1 sequence variant P117R (human)
presenilin-1 sequence variant P117A (human)
presenilin-1 sequence variant P117L (human)
presenilin-1 sequence variant E120K (human)
presenilin-1 sequence variant E120G (human)
presenilin-1 sequence variant E120D (human)
presenilin-1 sequence variant E123K (human)
presenilin-1 sequence variant N135D (human)
presenilin-1 sequence variant N135S (human)
presenilin-1 sequence variant A136G (human)
presenilin-1 sequence variant M139T (human)
presenilin-1 sequence variant M139V (human)
presenilin-1 sequence variant M139K (human)
presenilin-1 sequence variant M139I (human)
presenilin-1 sequence variant I143N (human)
presenilin-1 sequence variant I143V (human)
presenilin-1 sequence variant I143F (human)
presenilin-1 sequence variant I143T (human)
presenilin-1 sequence variant I143M (human)
presenilin-1 sequence variant M146L (human)
presenilin-1 sequence variant M146I (human)
presenilin-1 sequence variant M146V (human)
presenilin-1 sequence variant T147P (human)
presenilin-1 sequence variant T147I (human)
presenilin-1 sequence variant L153V (human)
presenilin-1 sequence variant Y154N (human)
presenilin-1 sequence variant Y154C (human)
presenilin-1 sequence variant H163Y (human)
presenilin-1 sequence variant H163R (human)
presenilin-1 sequence variant W165G (human)
presenilin-1 sequence variant W165C (human)
presenilin-1 sequence variant L166R (human)
presenilin-1 sequence variant L166P (human)
presenilin-1 sequence variant L166H (human)
presenilin-1 sequence variant L166del (human)
presenilin-1 sequence variant I167del (human)
presenilin-1 sequence variant I168del (human)
presenilin-1 sequence variant S169L (human)
presenilin-1 sequence variant S169P (human)
presenilin-1 sequence variant S170F (human)
presenilin-1 sequence variant L171P (human)
presenilin-1 sequence variant L173W (human)
presenilin-1 sequence variant L173F (human)
presenilin-1 sequence variant L174R (human)
presenilin-1 sequence variant L174M (human)
presenilin-1 sequence variant F177S (human)
presenilin-1 sequence variant F177L (human)
presenilin-1 sequence variant S178P (human)
presenilin-1 sequence variant G183V (human)
presenilin-1 sequence variant E184D (human)
presenilin-1 sequence variant G206A (human)
presenilin-1 sequence variant G206S (human)
presenilin-1 sequence variant G206V (human)
presenilin-1 sequence variant G206D (human)
presenilin-1 sequence variant G209E (human)
presenilin-1 sequence variant G209R (human)
presenilin-1 sequence variant G209V (human)
presenilin-1 sequence variant S212Y (human)
presenilin-1 sequence variant I213T (human)
presenilin-1 sequence variant I213F (human)
presenilin-1 sequence variant H214Y (human)
presenilin-1 sequence variant H214D (human)
presenilin-1 sequence variant G217D (human)
presenilin-1 sequence variant G217R (human)
presenilin-1 sequence variant L219F (human)
presenilin-1 sequence variant L219P (human)
presenilin-1 sequence variant Q222R (human)
presenilin-1 sequence variant Q222H (human)
presenilin-1 sequence variant Q223R (human)
presenilin-1 sequence variant L226R (human)
presenilin-1 sequence variant I229F (human)
presenilin-1 sequence variant A231V (human)
presenilin-1 sequence variant A231T (human)
presenilin-1 sequence variant M233L (human)
presenilin-1 sequence variant M233T (human)
presenilin-1 sequence variant M233I (human)
presenilin-1 sequence variant M233V (human)
presenilin-1 sequence variant L235P (human)
presenilin-1 sequence variant L235V (human)
presenilin-1 sequence variant F237L (human)
presenilin-1 sequence variant F237I (human)
presenilin-1 sequence variant I238M (human)
presenilin-1 sequence variant K239N (human)
presenilin-1 sequence variant T245P (human)
presenilin-1 sequence variant A246E (human)
presenilin-1 sequence variant L248R (human)
presenilin-1 sequence variant L248P (human)
presenilin-1 sequence variant L250S (human)
presenilin-1 sequence variant L250V (human)
presenilin-1 sequence variant Y256S (human)
presenilin-1 sequence variant A260V (human)
presenilin-1 sequence variant V261F (human)
presenilin-1 sequence variant V261L (human)
presenilin-1 sequence variant L262F (human)
presenilin-1 sequence variant C263R (human)
presenilin-1 sequence variant C263F (human)
presenilin-1 sequence variant P264L (human)
presenilin-1 sequence variant G266S (human)
presenilin-1 sequence variant P267S (human)
presenilin-1 sequence variant R269H (human)
presenilin-1 sequence variant R269G (human)
presenilin-1 sequence variant L271V (human)
presenilin-1 sequence variant V272A (human)
presenilin-1 sequence variant E273A (human)
presenilin-1 sequence variant T274R (human)
presenilin-1 sequence variant A275V (human)
presenilin-1 sequence variant R278I (human)
presenilin-1 sequence variant R278K (human)
presenilin-1 sequence variant R278T (human)
presenilin-1 sequence variant R278S (human)
presenilin-1 sequence variant E280A (human)
presenilin-1 sequence variant E280G (human)
presenilin-1 sequence variant L282V (human)
presenilin-1 sequence variant L282F (human)
presenilin-1 sequence variant L282R (human)
presenilin-1 sequence variant P284L (human)
presenilin-1 sequence variant P284S (human)
presenilin-1 sequence variant A285V (human)
presenilin-1 sequence variant L286V (human)
presenilin-1 sequence variant L286P (human)
presenilin-1 sequence variant T291P (human)
presenilin-1 sequence variant R358Q (human)
presenilin-1 sequence variant S365A (human)
presenilin-1 sequence variant R377M (human)
presenilin-1 sequence variant G378E (human)
presenilin-1 sequence variant G378V (human)
presenilin-1 sequence variant L381V (human)
presenilin-1 sequence variant L381F (human)
presenilin-1 sequence variant G384A (human)
presenilin-1 sequence variant F386S (human)
presenilin-1 sequence variant S390I (human)
presenilin-1 sequence variant V391F (human)
presenilin-1 sequence variant L392V (human)
presenilin-1 sequence variant L392P (human)
presenilin-1 sequence variant G394V (human)
presenilin-1 sequence variant N405S (human)
presenilin-1 sequence variant A409T (human)
presenilin-1 sequence variant C410Y (human)
presenilin-1 sequence variant L418F (human)
presenilin-1 sequence variant L420R (human)
presenilin-1 sequence variant L424H (human)
presenilin-1 sequence variant L424R (human)
presenilin-1 sequence variant L424F (human)
presenilin-1 sequence variant L424V (human)
presenilin-1 sequence variant A426P (human)
presenilin-1 sequence variant A431V (human)
presenilin-1 sequence variant A431E (human)
presenilin-1 sequence variant A434C (human)
presenilin-1 sequence variant A434T (human)
presenilin-1 sequence variant L435F (human)
presenilin-1 sequence variant P436S (human)
presenilin-1 sequence variant P436Q (human)
presenilin-1 sequence variant I439S (human)
presenilin-1 sequence variant T440del (human)
presenilin-2 sequence variant A85V (human)
presenilin-2 sequence variant T122P (human)
presenilin-2 sequence variant E126K (human)
presenilin-2 sequence variant N141I (human)
presenilin-2 sequence variant N141Y (human)
presenilin-2 sequence variant V148I (human)
presenilin-2 sequence variant S175C (human)
presenilin-2 sequence variant V214L (human)
presenilin-2 sequence variant Q228L (human)
presenilin-2 sequence variant M239V (human)
presenilin-2 sequence variant M239I (human)
presenilin-2 sequence variant T430M (human)
roundabout homolog 3 isoform ROBO3.1 (mouse)
roundabout homolog 3 isoform ROBO3.2 (mouse)
large ribosomal subunit protein uL13, initiator methionine removed acetylated and unphosphorylated 1
large ribosomal subunit protein uL13, initiator methionine removed acetylated and phosphorylated 1 (mouse)
bifunctional glutamate/proline--tRNA ligase phosphorylated 1 (mouse)
bifunctional glutamate/proline--tRNA ligase unphosphorylated 1 (mouse)
aminoacyl-tRNA synthetase multienzyme complex
interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human)
negative regulation of toll-like receptor 4 signaling pathway
zinc finger CCCH-type antiviral protein 1 isoform 3 prenylated-cysteine methyl ester-containing 1 (mouse)
STE20/SPS1-related proline-alanine-rich protein kinase isoform 3 (mouse)
positive regulation of mesenchymal cell proliferation
CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse)
Ceacam1a isoform Long glycosylated (mouse)
negative regulation of interleukin-2 production
negative regulation of T cell proliferation
CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse)
Bgp D glycosylated and phosphorylated (mouse)
Bgp1a/4L glycosylated and phosphorylated (mouse)
Ceacam1a isoform Long glycosylated and phosphorylated (mouse)
Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)
CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse)
Ceacam1a isoform Short glycosylated (mouse)
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
positive regulation of T cell proliferation
positive regulation of immunoglobulin production
positive regulation of activation-induced cell death of T cells
positive regulation of calcineurin-NFAT signaling cascade
positive regulation of CD4-positive, alpha-beta T cell activation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD8-positive, alpha-beta T cell activation
cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse)
host-mediated activation of viral process
cell adhesion molecule CEACAM1 sequence variant CEACAM1b (mouse)
host-mediated suppression of viral proces
host-mediated suppression of viral genome replication
CEACAM1a-4C1, signal peptide removed N-glycosylasparagine form (mouse)
CEACAM1a-2C1, signal peptide removed N-glycosylasparagine form (mouse)
CEACAM1a-2, signal peptide removed N-glycosylasparagine form (mouse)
CEACAM1b-2S, signal peptide removed N-glycosylasparagine form (mouse)
catenin beta-1 isoform 1 phosphorylated 12 (human)
positive regulation of transcription by RNA polymerase II
catenin beta-1 isoform 1 unphosphorylated 7 (human)
catenin beta-1 isoform 1 phosphorylated 13 (human)
appetite-regulating hormone isoform 1 mature O-octanoylated 1 (human)
appetite-regulating hormone isoform 1 mature non-octanoylated 1 (mouse)
CEACAM1a-2S, signal peptide removed N-glycosylasparagine form (mouse)
CEA-related cell adhesion molecule 1, isoform 1/2S glycosylated (mouse)
CEACAM1a-4 N-glycosylasparagine form (mouse)
CEACAM1a-2 N-glycosylasparagine form (mouse)
heat shock protein HSP 90-alpha, initiator methionine removed and K63-polyubiquitinated 1 (mouse)
thrombospondin-1, signal peptide removed form (mouse)
Note=Evidence on signal peptide removal is by curator inference based on PMID:8654563.
glycine receptor subunit alpha-3 isoform Alpha-3K (mouse)
neurotransmitter-gated ion channel clustering
gamma-aminobutyric acid receptor clustering
CEACAM1b-4, signal peptide removed N-glycosylasparagine form (mouse)
CEACAM1a-C1, signal peptide removed N-glycosylasparagine form (mouse)
tyrosine-protein kinase ABL1 phosphorylated 1 (human)
14-3-3 protein zeta/delta phosphorylated 1 (human)
14-3-3 protein zeta/delta unphosphorylated 1 (human)
catenin beta-1 isoform 1 phosphorylated 14 (human)
heat shock protein HSP 90-alpha, initiator methionine removed non-ubiquitinated 1 (mouse)
voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 (mouse)
interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
interleukin-6-mediated signaling pathway
presenilin-1 sequence variant F386I (human)
presenilin-1 sequence variant F388L (human)
presenilin-1 sequence variant G209A (human)
presenilin-1 sequence variant H214N (human)
presenilin-1 sequence variant I408T (human)
presenilin-1 sequence variant N135Y (human)
presenilin-1 sequence variant P267A (human)
presenilin-1 sequence variant R220P (human)
presenilin-1 sequence variant S169del (human)
presenilin-2 sequence variant G212V (human)
presenilin-2 sequence variant L238P (human)
triggering receptor expressed on myeloid cells 2 sequence variant D134G (human)
UniProtKB:Q9NZC2-1, Asp-134, CHEBI:29947
triggering receptor expressed on myeloid cells 2 sequence variant K186N (human)
UniProtKB:Q9NZC2-1, Lys-186, CHEBI:50347
Rho-associated protein kinase 1 isoform 1 unmodified form (human)
triggering receptor expressed on myeloid cells 2 sequence variant V126G (human)
UniProtKB:Q9NZC2-1, Val-126, CHEBI:29947
triggering receptor expressed on myeloid cells 2 sequence variant W44* (human)
triggering receptor expressed on myeloid cells 2 sequence variant W50C (human)
triggering receptor expressed on myeloid cells 2 sequence variant W78* (human)
voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)
Bcl-2-like protein 11 isoform 2 unmodified form (human)
Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse)
Bcl2-associated agonist of cell death isoform 1 unmodified form (rat)
Evidence=Treatment with L-Glutamate induces dephosphorylation and binding to BCL-XL. Evidence=Fig4B.
Bcl2-associated agonist of cell death isoform 2 unmodified form (human)
M protein (Dengue virus 2 Thailand/16681/84)
NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (Dengue virus 2 Thailand/NGS-C/1944)
negative regulation of type I interferon-mediated signaling pathway
NS2B (Dengue virus 2 Thailand/NGS-C/1944)
positive regulation of serine-type endopeptidase activity
NS3 (Dengue virus 2 Thailand/NGS-C/1944)
ribonucleoside triphosphate phosphatase activity
NS4A (Dengue virus 2 Thailand/NGS-C/1944)
protein insertion into ER membrane by internal uncleaved signal-anchor sequence
NS4B (Dengue virus 2 Thailand/NGS-C/1944)
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
NS5 (Dengue virus 2 Thailand/NGS-C/1944)
symbiont-mediated evasion of host immune response
prM (Dengue virus 2 Thailand/NGS-C/1944)
thrombospondin-2 isoform 1 cleaved 2 (human)
thrombospondin-2 isoform 1 cleaved 3 (human)
envelope glycoprotein gp120 N-glycosylated 1 (Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF))
Note=DC-SIGN seems critical for whether HIV is bound and targeted to the endolysosomal pathway
eIF-2-alpha kinase GCN2 isoform 1 phosphorylated form (mouse)
cytokine receptor common subunit beta isoform 1 phosphorylated 1 (human)
CSF2RB isoform 1 phosphorylated 1 (human)
F-box only protein 4 isoform 1 phosphorylated 1 (human)
FBXO4 isoform 1 phosphorylated 1 (human)
kinase suppressor of Ras 1 phosphorylated 1 (mouse)
phosphofurin acidic cluster sorting protein 2 phosphorylated 1 (human)
serine/threonine-protein kinase PLK1 phosphorylated 1 (human)
metaphase/anaphase transition of mitotic cell cycle
serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human)
neuregulin-1 type I-beta1a mature form (mouse)
neuregulin-1 type III-beta1a transmembrane precursor (mouse)
neuregulin type III-beta1a precursor (mouse)
pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 1 (human)
pyruvate dehydrogenase (acetyl-transferring) activity
pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 2 (human)
pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 3 (human)
pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial inactive (human)
catalase-3 phosphorylated 1 (Arabidopsis thaliana)
NAD(P)H-hydrate epimerase isoform 2 (mouse)
AD(P)H-hydrate epimerase precursor short form (mouse)
positive regulation of dendritic spine development
positive regulation of protein localization to cell surface
neuregulin-1 intracellular domain (mouse)
histone H1.4, initiator methionine removed monomethylated 1 (human)
histone H2A type 1-G/I/K/L/M, initiator methionine removed phosphorylated 2 (human)
DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (human)
E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human)
cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human)
smad2 isoform Long unphosphorylated 1 (human)
endonuclease 8-like 2 isoform 1 unacetylated 1 (human)
endonuclease 8-like 2 isoform 1 unmodified form (human)
DNA polymerase beta unacetylated 1 (human)
DNA polymerase beta unmodified form (human)
SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 non-myristoylated 1 (mouse)
DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (rat)
cyclic nucleotide-gated channel alpha-1 isoform 1 unphosphorylated 1 (cow)
voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)
voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human)
A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse)
A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A unglycosylated 1 (human)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A unphosphorylated form (human)
histone H1.4, initiator methionine removed monomethylated and phosphorylated 1 (human)
microtubule-associated protein tau sequence variant S285R (human)
presenilin-1 sequence variant I83T (human)
presenilin-1 sequence variant T116R (human)
presenilin-1 sequence variant L134R (human)
presenilin-1 sequence variant L150P (human)
presenilin-1 sequence variant A164V (human)
presenilin-1 sequence variant L166V (human)
presenilin-1 sequence variant E184G (human)
presenilin-1 sequence variant I202F (human)
presenilin-1 sequence variant L226F (human)
presenilin-1 sequence variant S230R (human)
presenilin-1 sequence variant S230I (human)
presenilin-1 sequence variant A231P (human)
presenilin-1 sequence variant L235R (human)
presenilin-1 sequence variant A246P (human)
presenilin-1 sequence variant L262V (human)
presenilin-1 sequence variant E273G (human)
presenilin-1 sequence variant E280K (human)
presenilin-1 sequence variant R377W (human)
presenilin-1 sequence variant S390N (human)
presenilin-1 sequence variant A396T (human)
presenilin-1 sequence variant I437V (human)
presenilin-2 sequence variant K161R (human)
breast cancer type 2 susceptibility protein phosphorylated 2 (human)
dual specificity protein kinase TTK phosphorylated 1 (human)
ribosomal protein S6 kinase alpha-6 phosphorylated 1 (human)
sugar transport protein 13 phosphorylated 1 (Arabidopsis thaliana)
monosaccharide transmembrane transporter activity
TTK activation loop phosphorylated form (human)
TTK activation loop and P+1 loop phosphorylated form (human)
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human)
platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human)
epidermal growth factor receptor, signal peptide removed phosphorylated 3 (human)
epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human)
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
protein kinase C theta type phosphorylated 4 (human)
DAZ-associated protein 1 acetylated 1 (human)
receptor-type tyrosine-protein phosphatase C isoform x1 (mouse)
receptor-type tyrosine-protein phosphatase C isoform B220 (mouse)
Toll/IL-1 recepter (TIR)-domain containing adapter inducing interferon beta (chicken)
mediator of RNA polymerase II transcription subunit 14 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 12 isoform 1 (mouse)
patatin-like phospholipase domain-containing protein 7 isoform 1 (mouse)
phosphatidylcholine lysophospholipase activity
patatin-like phospholipase domain-containing protein 7 isoform 2 (mouse)
patatin-like phospholipase domain-containing protein 7 isoform 3 (mouse)
neuropathy target esterase-related esterase splice variant 2 (mouse)
cation channel sperm-associated protein 2 (mouse)
cilium or flagellum-dependent cell motility
cation channel sperm-associated protein 2 isoform m1 (mouse)
cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse)
Purkinje cell protein 2 isoform 2 (mouse)
granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 2 (mouse)
GM-CSF receptor alpha subunit isoform 2 (mouse)
GM-CSF receptor alpha-chain isoform 2 (mouse)
cellular response to granulocyte macrophage colony-stimulating factor stimulus
granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 3 (mouse)
GM-CSF receptor alpha subunit isoform 3 (mouse)
GM-CSF receptor alpha-chain isoform 3 (mouse)
selection and upkeep of intraepithelial T-cells protein 2 isoform 4 (mouse)
small conductance calcium-activated potassium channel protein 2 isoform 3 (mouse)
corticotropin-releasing factor receptor 2 isoform iv-beta (mouse)
positive regulation of cAMP-mediated signaling
negative regulation of cAMP-mediated signaling
roundabout homolog 3 isoform ROBO3A.1 (mouse)
retinoic acid receptor RXR-gamma isoform 2 (mouse)
STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse)
negative regulation of potassium ion transmembrane transport
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse)
phosphoinositide phospholipase C (mouse)
carbohydrate-responsive element-binding protein isoform 6 (mouse)
carbohydrate-responsive element-binding protein isoform beta (mouse)
bone morphogenetic protein receptor type-1B isoform 1 (human)
left-right determination factor 2 isoform 1 (human)
syntaxin-binding protein 1 isoform 1 (mouse)
negative regulation of synaptic transmission, GABAergic
microsomal triglyceride transfer protein large subunit isoform 1 (mouse)
microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)
microsomal triglyceride transfer protein large subunit isoform 2 (mouse)
microsomal triglyceride transfer protein large subunit isoform MTP-B (mouse)
microsomal triglyceride transfer protein large subunit isoform MTPv1 (mouse)
mitotic checkpoint serine/threonine-protein kinase BUB1 (mouse)
Timing=prometaphase and metaphase of Meiosis I
negative regulation of programmed cell death
segment polarity protein dishevelled homolog DVL-2 (human)
highly expressed in cancer protein (human)
kinetochore-associated protein 2 (human)
retinoblastoma-associated protein HEC (human)
serine/threonine-protein kinase 15 (human)
serine/threonine-protein kinase 6 (human)
serine/threonine-protein kinase aurora-A (human)
chromosome region maintenance 1 protein homolog (human)
mothers against decapentaplegic homolog 7 isoform 1 (human)
baculoviral IAP repeat-containing protein 5 (human)
Target=PR:Q96GD4. Target=PR:Q9NQS7. Target=PR:Q53HL2.
intermediate conductance calcium-activated potassium channel protein 4 (human)
intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (human)
protein BRASSINOSTEROID INSENSITIVE 1 (Arabidopsis thaliana)
brassinosteroid LRR receptor kinase (Arabidopsis thaliana)
CBL-interacting serine/threonine-protein kinase 11 (Arabidopsis thaliana)
SNF1-related kinase 3.22 (Arabidopsis thaliana)
SOS2-like protein kinase PKS5 (Arabidopsis thaliana)
SOS3-interacting protein 4 (Arabidopsis thaliana)
Target=PR:Q8LAS7. Evidence=ECO:0000178.
protein ETHYLENE INSENSITIVE 3 (Arabidopsis thaliana)
regulation of ethylene-activated signaling pathway
Bcl2-associated agonist of cell death isoform Alpha (rat)
Bcl2-associated agonist of cell death isoform Beta (rat)
potassium voltage-gated channel subfamily S member 1 isoform 1 (mouse)
potassium voltage-gated channel subfamily S member 2 isoform 1 (mouse)
mothers against decapentaplegic homolog 6 isoform 1 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A (mouse)
potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)
potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse)
Timing=unfertilized oocytes and right after fertilization
voltage-gated inwardly rectifying potassium channel KCNH2 isoform 1A' (mouse)
potassium voltage-gated channel subfamily H member 2 isoform 2 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform B (mouse)
potassium voltage-gated channel subfamily H member 2 isoform 1B (mouse)
potassium voltage-gated channel subfamily H member 2 isoform 3 (mouse)
pre-B-cell leukemia transcription factor 3 isoform 1 (mouse)
X-box-binding protein 1 isoform 2 (mouse)
RNA polymerase II-specific DNA-binding transcription factor binding
positive regulation of proteasomal protein catabolic process
bone morphogenetic protein receptor type-2 isoform 1 (mouse)
zinc finger protein ZFPM1 isoform 1 (mouse)
negative regulation of Wnt signaling pathway
long chain base biosynthesis protein 1 (mouse)
serine-palmitoyl-CoA transferase 1 (mouse)
serine palmitoyltransferase 1 isoform 1 (mouse)
suppressor of cytokine signaling 1 (mouse)
centromere/kinetochore protein zw10 homolog (human)
Bcl-2-like protein 11 isoform BimL (human)
Bcl-2-like protein 11 isoform Bim(L) (human)
potassium voltage-gated channel subfamily KQT member 3 (human)
potassium channel subunit alpha KvLQT3 (human)
voltage-gated potassium channel subunit Kv7.3 (human)
potassium voltage-gated channel subfamily KQT member 2 isoform 2 (human)
potassium voltage-gated channel subfamily KQT member 2 isoform 4 (human)
potassium voltage-gated channel subfamily KQT member 2 isoform 6 (human)
potassium voltage-gated channel subfamily KQT member 2 isoform HNSPC (human)
mothers against decapentaplegic homolog 6 isoform A (human)
mothers against decapentaplegic homolog 6 isoform B (human)
mothers against decapentaplegic homolog 6 isoform Smad 6S (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 (human)
Note=Interaction observed through out the cell cycle.
Note=Interaction observed in nocodazole.
Timing=Mitosis (prophase, prometaphase, metaphase) and spindle disruption (nocodazole). Localization is increased by PR:Q9NQS7.
Timing=Mitosis (prophase, pro-metaphase, metaphase).
serine/threonine-protein kinase BIK1 isoform 1 (Arabidopsis thaliana)
NKG2-D type II integral membrane protein isoform 1 (mouse)
NKG2-D type II integral membrane protein isoform NKG2D long (mouse)
NKG2-D type II integral membrane protein isoform NKG2D-L (mouse)
NKG2-D type II integral membrane protein isoform 2 (mouse)
NKG2-D type II integral membrane protein isoform NKG2D short (mouse)
NKG2-D type II integral membrane protein isoform NKG2D-S (mouse)
regulator of G-protein signaling 9 isoform 1 (mouse)
regulator of G-protein signaling 9 isoform RGS9-1 (mouse)
vascular endothelial growth factor receptor 1 isoform 2 (mouse)
DNA repair protein RAD51 homolog 4 isoform 1 (mouse)
mitotic spindle checkpoint component mad3 (Schizosaccharomyces pombe 972h-)
mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human)
MAD3/BUB1-related protein kinase (human)
Note=Interaction occurs under nocodazole treatment. Kinetochore localization increased in this condition.
Timing=spindle depolymerization (nocodazole).
ubiquitin-protein transferase inhibitor activity
Timing=Mitosis (prophase, prometaphase, metaphase). Kinetochore localization increased by O43683 (Bub1).
negative regulation of ubiquitin-protein transferase activity
positive regulation of attachment of spindle microtubules to kinetochore
E3 ubiquitin-protein ligase TRIM13 isoform 1 (human)
phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 1 (mouse)
phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 2 (mouse)
Rho-associated protein kinase 2 isoform 1 (human)
DNA (cytosine-5)-methyltransferase 3B isoform 1 (mouse)
DNA (cytosine-5)-methyltransferase 3B isoform 5 (mouse)
catechol O-methyltransferase isoform 1 (mouse)
catechol O-methyltransferase isoform 2 (mouse)
catechol-containing compound metabolic process
ubiquitin carboxyl-terminal hydrolase 2 isoform 1 (mouse)
ubiquitin carboxyl-terminal hydrolase 2 isoform 2 (mouse)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 (mouse)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)
negative regulation of transcription by RNA polymerase II
negative regulation of keratinocyte differentiation
adhesion G protein-coupled receptor L1 isoform 2 (rat)
adhesion G protein-coupled receptor L1 isoform CL1AA (rat)
adhesion G protein-coupled receptor L1 isoform 3 (rat)
adhesion G protein-coupled receptor L1 isoform CL1AB (rat)
adhesion G protein-coupled receptor L1 isoform 4 (rat)
adhesion G protein-coupled receptor L1 isoform CL1BA (rat)
potassium voltage-gated channel subfamily KQT member 2 isoform A (rat)
negative regulation of amyloid-beta formation
fibroblast growth factor 14 isoform 3 (mouse)
positive regulation of high voltage-gated calcium channel activity
intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (mouse)
positive regulation of protein secretion
spindle assembly checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-)
voltage-gated delayed rectifier potassium channel KCNH1 isoform 1 (human)
potassium voltage-gated channel subfamily H member 1 isoform hEAG (human)
zinc finger FYVE domain-containing protein 9 isoform 1 (human)
regulation of SMAD protein signal transduction
zinc finger FYVE domain-containing protein 9 isoform 2 (human)
zinc finger FYVE domain-containing protein 9 isoform 3 (human)
nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human)
Note=Binding to CRM1 increases when coexpressed with calcineurin and JIP-1
L-lactate dehydrogenase C chain isoform 1 (mouse)
transforming growth factor beta-1 isoform 1 (human)
Note=Annotation from GAF, isoform mapped to PRO
Muellerian-inhibiting factor isoform 1 (human)
RAF proto-oncogene serine/threonine-protein kinase (human)
positive regulation of DNA endoreduplication
transforming growth factor beta-1 isoform 1 (mouse)
cellular tumor antigen p53 isoform 1 (human)
Timing=metaphase and spindle depolymerization (nocodazole)
transcription factor AP-2-alpha isoform 1 (human)
transcription factor AP-2-alpha isoform 4 (human)
V-jun avian sarcoma virus 17 oncogene homolog (mouse)
protein kinase C beta type isoform Beta-I (human)
protein kinase C beta type isoform PRKCB1 (human)
protein kinase C beta type isoform Beta-II (human)
protein kinase C beta type isoform PRKCB2 (human)
glucocorticoid receptor isoform 2 (mouse)
glucocorticoid receptor isoform 2-A (mouse)
glucocorticoid receptor isoform GR form B (mouse)
negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
2-phospho-D-glycerate hydro-lyase (human)
transcription factor Sp1 isoform 1 (human)
transcription factor Sp1 isoform Sp1a (human)
E3 SUMO-protein transferase ERG2 (mouse)
E3 SUMO-protein ligase EGR2 isoform Long (mouse)
E3 SUMO-protein ligase EGR2 isoform Short (mouse)
sensor protein CreC isoform 1 (Escherichia coli K-12)
monocyte differentiation antigen CD14 (human)
myeloid cell-specific leucine-rich glycoprotein (human)
homeobox protein Hox-A9 isoform HoxA-9 (mouse)
homeobox protein Hox-A9 isoform HoxA-9T (mouse)
glycogen phosphorylase (Escherichia coli K-12)
cGMP-dependent protein kinase 1 isoform Alpha (mouse)
cGMP-dependent protein kinase 1 isoform CGK1-alpha (mouse)
chemokine (C-X-C motif) ligand 8 (human)
granulocyte chemotactic protein 1 (human)
monocyte-derived neutrophil chemotactic factor (human)
monocyte-derived neutrophil-activating peptide (human)
apoptosis regulator Bcl-2 isoform Alpha (human)
negative regulation of calcineurin-NFAT signaling cascade
apoptosis regulator Bcl-2 isoform Alpha (mouse)
transforming growth factor beta-3 isoform 1 (human)
ribosomal protein S6 kinase 2 alpha (frog)
MAP kinase-activated protein kinase 1 (frog)
ribosomal protein S6 kinase II alpha (frog)
monocyte differentiation antigen CD14 (mouse)
myeloid cell-specific leucine-rich glycoprotein (mouse)
nitrate reductase [NADH] 2 (Arabidopsis thaliana)
nuclear receptor subfamily 1 group B member 1 (mouse)
regulation of granulocyte differentiation
ventricular cardiac muscle cell differentiation
retinoic acid receptor alpha isoform 1 (mouse)
RNA polymerase II transcription regulatory region sequence-specific DNA binding
negative regulation of translational initiation
bone morphogenetic protein 2 isoform 1 (human)
bone morphogenetic protein 4 isoform 1 (human)
cystic fibrosis transmembrane conductance regulator isoform 3 (human)
interleukin-1 receptor-like 1 isoform A (mouse)
interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)
interleukin-1 receptor-like 1 isoform ST2L (mouse)
interleukin-1 receptor-like 1 isoform B (mouse)
interleukin-1 receptor-like 1 isoform Soluble (mouse)
interleukin-1 receptor-like 1 isoform ST2 (mouse)
negative regulation of canonical NF-kappaB signal transduction
BDNF/NT-3 growth factors receptor isoform 1 (mouse)
BDNF/NT-3 growth factors receptor isoform 2 (mouse)
beta-1,4-galactosyltransferase 1 isoform 1 (mouse)
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
branching morphogenesis of an epithelial tube
positive regulation of apoptotic process involved in mammary gland involution
potassium voltage-gated channel subfamily A member 2 isoform 1 (human)
transforming growth factor beta-3 isoform 1 (mouse)
erythroid transcription factor isoform 1 (mouse)
erythroid transcription factor isoform 2 (mouse)
bone morphogenetic protein 7 isoform 1 (human)
interleukin-1 receptor antagonist protein isoform 2 (human)
interleukin-1 receptor antagonist protein isoform icIL-1ra (human)
Note=In response to P2RX7 receptor or ATP stimulation
interleukin-1 receptor antagonist protein isoform 3 (human)
interleukin-1 receptor antagonist protein isoform icIL-1ra type II (human)
interleukin-1 receptor antagonist protein isoform 4 (human)
cationic amino acid transporter 2 isoform 1 (mouse)
cationic amino acid transporter 2 isoform Alpha (mouse)
L-ornithine transmembrane transporter activity
L-lysine transmembrane transporter activity
low-affinity L-arginine transmembrane transporter activity
L-arginine import across plasma membrane
cationic amino acid transporter 2 isoform 2 (mouse)
cationic amino acid transporter 2 isoform Beta (mouse)
high-affinity L-arginine transmembrane transporter activity
high-affinity lysine transmembrane transporter activity
high-affinity L-ornithine transmembrane transporter activity
L-ornithine import across plasma membrane
retinoic acid receptor gamma isoform 1 (mouse)
retinoic acid receptor gamma isoform A (mouse)
retinoic acid receptor gamma isoform 2 (mouse)
retinoic acid receptor gamma isoform B (mouse)
lymphocyte function-associated antigen 3 (human)
DNA-binding protein inhibitor ID-1 (mouse)
POU domain, class 5, transcription factor 1 isoform 1 (mouse)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
tumor necrosis factor receptor superfamily member 9 isoform 1 (mouse)
bone morphogenetic protein 6 isoform 1 (mouse)
bone morphogenetic protein 2 isoform 1 (mouse)
potassium voltage-gated channel subfamily A member 3 isoform 1 (human)
bone morphogenetic protein 6 isoform 1 (human)
interleukin-6 receptor subunit alpha isoform 1 (mouse)
myeloid differentiation primary response protein MyD88 isoform 2 (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 1 (human)
potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat)
potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat)
Note=Correct species assignment not stated, but can be discerned from sequence shown in PMID:10414303
Wilms tumor protein homolog isoform 1 (mouse)
Wilms tumor protein homolog isoform 2 (mouse)
Wilms tumor protein homolog isoform 4 (mouse)
retinoic acid receptor beta isoform 1 (mouse)
retinoic acid receptor beta isoform 3 (mouse)
odontogenesis of dentin-containing tooth
bone morphogenetic protein 7 isoform 1 (mouse)
ribosomal protein S6 kinase beta-1 isoform Alpha I (human)
ribosomal protein S6 kinase beta-1 isoform p80-S6K 1 (human)
ribosomal protein S6 kinase beta-1 isoform Alpha II (human)
nuclear transcription factor Y subunit alpha isoform 2 (mouse)
nuclear transcription factor Y subunit alpha isoform short (mouse)
regulation of stem cell population maintenance
positive regulation of stem cell proliferation
adenomatous polyposis coli protein (human)
Timing=Mitosis (prometaphase, metaphase, NOT prophase).
interleukin-1 receptor antagonist protein isoform 2 (mouse)
voltage-gated potassium channel KCNC1 isoform Long (rat)
potassium voltage-gated channel subfamily C member 1 isoform 1 (rat)
voltage-gated potassium channel KCNC1 isoform Short (rat)
potassium voltage-gated channel subfamily C member 1 isoform 2 (rat)
POU domain, class 2, transcription factor 1 isoform 10 (mouse)
POU domain, class 2, transcription factor 1 isoform OCT-1Z (mouse)
POU domain, class 2, transcription factor 1 isoform 2 (mouse)
POU domain, class 2, transcription factor 1 isoform OCT-1B (mouse)
tumor necrosis factor receptor superfamily member 6 isoform 1 (human)
nucleolar transcription factor 1 isoform UBF1 (mouse)
nucleolar transcription factor 1 isoform Long (mouse)
nucleolar transcription factor 1 isoform UBF2 (mouse)
nucleolar transcription factor 1 isoform Short (mouse)
spindle assembly checkpoint protein BUB3 (yeast)
activin receptor type-2A isoform 1 (mouse)
activin receptor type-2B isoform ActR-IIB1 (mouse)
activin receptor type-2B isoform ActR-IIB3 (mouse)
activin receptor type-2B isoform ActR-IIB4 (mouse)
mitogen-activated protein kinase 3 isoform 1 (human)
mitogen-activated protein kinase 1 isoform 1 (human)
50 kDa nuclear polyadenylated RNA-binding protein (mouse)
CUG triplet repeat RNA-binding protein 1 (mouse)
embryo deadenylation element-binding protein homolog (mouse)
retinoic acid receptor RXR-alpha isoform 1 (mouse)
retinoic acid receptor RXR-beta isoform Short (mouse)
RNA polymerase II cis-regulatory region sequence-specific DNA binding
retinoic acid receptor signaling pathway
retinoic acid receptor RXR-gamma isoform 1 (mouse)
retinoblastoma-like protein 1 isoform 1 (human)
transcription factor PML isoform 1 (human)
transcription factor PML isoform 2 (human)
positive regulation of defense response to virus by host
transcription factor PML isoform 3 (human)
negative regulation of mitotic cell cycle
transcription factor PML isoform 4 (human)
transcription factor PML isoform 5 (human)
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of translation in response to oxidative stress
cyclic nucleotide-gated channel alpha-1 isoform 1 (human)
cyclic nucleotide-gated channel alpha-1 (mouse)
cyclic nucleotide-gated cation channel 1 (mouse)
cyclic nucleotide-gated channel, photoreceptor (mouse)
rod photoreceptor cGMP-gated channel subunit alpha (mouse)
prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)
D(3) dopamine receptor isoform D3Short (mouse)
dopamine neurotransmitter receptor activity, coupled via Gi/Go
signal transduction histidine-protein kinase BaeS isoform 1 (Escherichia coli K-12)
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 (mouse)
carcinoembryonic antigen-related cell adhesion molecule 1 isoform Bgpc (mouse)
carcinoembryonic antigen-related cell adhesion molecule 1 isoform Ceacam1-2S (mouse)
CEA-related cell adhesion molecule 1, isoform 1/2S (mouse)
homophilic cell adhesion via plasma membrane adhesion molecules
72 kDa type IV collagenase isoform 1 (mouse)
72 kDa type IV collagenase isoform 2 (mouse)
dual specificity protein kinase TTK (human)
phosphotyrosine picked threonine-protein kinase (human)
negative regulation of mitotic metaphase/anaphase transition
bone morphogenetic protein 8B isoform 1 (human)
bone morphogenetic protein 8A isoform 1 (mouse)
glutamate receptor ionotropic, NMDA 1 isoform long (mouse)
Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)
proto-oncogene tyrosine-protein kinase receptor Ret isoform 2 (mouse)
transcription factor SOX-5 isoform 2 (mouse)
transcription factor SOX-5 isoform 3 (mouse)
vascular endothelial growth factor receptor 1 (mouse)
tyrosine-protein kinase receptor FLT (mouse)
branching involved in blood vessel morphogenesis
vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor receptor 1 isoform 1 (mouse)
bone morphogenetic protein receptor type-1A isoform 1 (human)
bone morphogenetic protein receptor type-1A isoform 1 (mouse)
activin receptor type-1B isoform 1 (human)
activin receptor type-1B isoform SKR2-1 (human)
activin receptor type-1B isoform 2 (human)
activin receptor type-1B isoform SKR2-2 (human)
activin receptor type-1B isoform 3 (human)
activin receptor type-1B isoform SKR2-3 (human)
TGF-beta receptor type-1 isoform 1 (human)
bone morphogenetic protein receptor type-1B isoform 1 (mouse)
activin receptor type-1-like isoform 1 (human)
TGF-beta receptor type-2 isoform RII-2 (human)
TGF-beta receptor type-2 isoform 2 (human)
peroxisome proliferator-activated receptor gamma isoform 1 (mouse)
positive regulation of fat cell differentiation
hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (mouse)
breast cancer type 1 susceptibility protein isoform 5 (human)
glutamate receptor ionotropic, kainate 2 isoform 1 (mouse)
glutamate receptor ionotropic, kainate 2 isoform 2 (mouse)
sensor protein TorS isoform 1 (Escherichia coli K-12)
vacuolar protein sorting-associated protein 26A isoform 1 (mouse)
vacuolar protein sorting-associated protein 26A isoform 2 (mouse)
von Hippel-Lindau disease tumor suppressor isoform 3 (human)
peroxisomal biogenesis factor 19 isoform 1 (human)
peroxisomal biogenesis factor 19 isoform 2 (human)
peroxisomal biogenesis factor 19 isoform 4 (human)
mitotic spindle checkpoint component MAD2 (yeast)
tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse)
tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse)
DNA-binding protein inhibitor ID-3 isoform 1 (mouse)
DNA-binding protein inhibitor ID-1 (human)
class B basic helix-loop-helix protein 24 (human)
DNA-binding protein inhibitor ID-1 isoform ID-A (human)
DNA-binding protein inhibitor ID-2 isoform 1 (mouse)
DNA-binding protein inhibitor ID-4 isoform 1 (mouse)
negative regulation of neuron differentiation
spindle assembly checkpoint serine/threonine-protein kinase BUB1 (yeast)
serine/threonine-protein kinase mTOR (human)
FK506-binding protein 12-rapamycin complex-associated protein 1 (human)
FKBP12-rapamycin complex-associated protein (human)
cyclin-dependent kinase 4 inhibitor B isoform 1 (human)
cyclin-dependent kinase 4 inhibitor B isoform p15 (human)
growth/differentiation factor 5 isoform 1 (human)
heterochromatin protein 1 homolog alpha (human)
spindle assembly checkpoint component MAD3 (yeast)
F-actin-capping protein subunit beta isoform 1 (mouse)
regulation of protein kinase C signaling
F-actin-capping protein subunit beta isoform 2 (mouse)
negative regulation of microtubule polymerization
F-actin-capping protein subunit beta isoform Capzb3 (mouse)
mitogen-activated protein kinase 14 isoform 1 (mouse)
myoblast differentiation involved in skeletal muscle regeneration
ATP-dependent 6-phosphofructokinase, muscle type isoform 1 (mouse)
DNA-binding protein inhibitor ID-4 isoform 1 (human)
regulated endocrine-specific protein 18 isoform 1 (mouse)
tumor necrosis factor ligand superfamily member 6 isoform FasL (human)
tumor necrosis factor ligand superfamily member 6 isoform 1 (human)
natural resistance-associated macrophage protein 2 (mouse)
solute carrier family 11 member 2 (mouse)
porphyrin-containing compound metabolic process
multicellular organismal-level iron ion homeostasis
natural resistance-associated macrophage protein 2 isoform 2 (mouse)
natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse)
proton transmembrane transporter activity
cobalt ion transmembrane transporter activity
ferrous iron transmembrane transporter activity
natural resistance-associated macrophage protein 2 isoform 1 (mouse)
natural resistance-associated macrophage protein 2 isoform IRE (mouse)
iron ion transmembrane transporter activity
histone H3-like centromeric protein A (human)
cartilage oligomeric matrix protein isoform 1 (human)
vascular endothelial growth factor B isoform VEGF-B167 (mouse)
fms-related tyrosine kinase 3 ligand isoform 1 (mouse)
fms-related tyrosine kinase 3 ligand isoform 2 (mouse)
fms-related tyrosine kinase 3 ligand isoform 3 (mouse)
breast cancer type 2 susceptibility protein (human)
interleukin-1 receptor-associated kinase 1 isoform 1 (human)
interleukin-1 receptor-associated kinase 1 isoform a (human)
potassium voltage-gated channel subfamily KQT member 1 isoform 1 (human)
potassium voltage-gated channel subfamily KQT member 1 isoform 2 (human)
potassium voltage-gated channel subfamily KQT member 1 isoform TKvLQT1 (human)
negative regulation of potassium ion transport
serine/threonine-protein kinase PLK1 (human)
serine/threonine-protein kinase 13 (human)
Timing=Mitosis and spindle disruption (nocodazole). Localization increased by PR:000035412 and PR:Q9NQS7.
negative regulation of maintenance of sister chromatid cohesion
serine/threonine-protein kinase MPS1 (yeast)
regulatory cell proliferation kinase 1 (yeast)
solute carrier family 12 member 1 isoform A (mouse)
solute carrier family 12 member 1 isoform F (mouse)
solute carrier family 12 member 1 isoform C9 (mouse)
sodium:potassium:chloride symporter activity
bone morphogenetic protein 8B isoform 1 (mouse)
small conductance calcium-activated potassium channel protein 2 isoform 1 (mouse)
Toll/interleukin-1 receptor domain-containing adapter protein isoform 2 (human)
phosphatidylinositol-4,5-bisphosphate binding
myelin proteolipid protein isoform DM-20 (mouse)
D(2) dopamine receptor isoform 1 (mouse)
adenylate cyclase-inhibiting dopamine receptor signaling pathway
G protein-coupled dopamine receptor signaling pathway
regulation of synaptic transmission, GABAergic
D(2) dopamine receptor isoform 2 (mouse)
negative regulation of synaptic transmission, glutamatergic
negative regulation of dopamine receptor signaling pathway
transforming growth factor beta-2 isoform A (human)
transforming growth factor beta-2 isoform B (human)
14-3-3 protein epsilon isoform 1 (human)
TSC22 domain family protein 1 isoform 2 (mouse)
E3 ubiquitin-protein ligase RBX1 isoform 1 (human)
guanine nucleotide-binding protein subunit beta-5 isoform 1 (mouse)
guanine nucleotide-binding protein subunit beta-5 isoform Beta-5L (mouse)
guanine nucleotide-binding protein subunit beta-5 isoform Gbeta5L (mouse)
guanine nucleotide-binding protein subunit beta-5 isoform Long (mouse)
paired box protein Pax-6 isoform 1 (mouse)
paired box protein Pax-6 isoform 1 (rat)
paired box protein Pax-6 isoform 2 (rat)
nuclear receptor subfamily 1 group A member 1 (mouse)
thyroid hormone receptor alpha isoform Alpha-2 (mouse)
thyroid hormone receptor alpha isoform Alpha-1 (mouse)
steroid receptor RNA activator RNA binding
thyroid hormone receptor alpha isoform Alpha-deltaE6 (mouse)
positive regulation of myotube differentiation
mitogen-activated protein kinase 1 isoform 1 (mouse)
protein kinase C inhibitor protein 1 (human)
potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)
Note=Binding to DLG4 from different organism
S-phase kinase-associated protein 1 isoform 1 (human)
chaperone protein ClpB isoform 1 (Escherichia coli K-12)
chaperone protein ClpB isoform ClpB (Escherichia coli K-12)
clpB isoform ClpB (Escherichia coli K-12)
chaperone protein ClpB isoform 2 (Escherichia coli K-12)
chaperone protein ClpB isoform ClpB-3 (Escherichia coli K-12)
clpB isoform ClpB-3 (Escherichia coli K-12)
transient receptor potential cation channel subfamily V member 5 (mouse)
ATP-binding cassette sub-family C member 9 isoform 1 (mouse)
F-actin-capping protein subunit alpha-3 (mouse)
Rho-associated protein kinase 2 isoform 2 (mouse)
rho-associated protein kinase 2 isoform ROCK2m (mouse)
positive regulation of muscle cell differentiation
mothers against decapentaplegic homolog 1 isoform 1 (mouse)
short stature homeobox protein 2 isoform 1 (mouse)
short stature homeobox protein 2 isoform OG12A (mouse)
short stature homeobox protein 2 isoform PRX3A (mouse)
short stature homeobox protein 2 isoform 2 (mouse)
short stature homeobox protein 2 isoform OG12B (mouse)
short stature homeobox protein 2 isoform PRX3B (mouse)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse)
BH3-interacting domain death agonist isoform 1 (mouse)
interferon regulatory factor 3 isoform 1 (mouse)
sensor-like histidine kinase YedV isoform 1 (Escherichia coli K-12)
tyrosine-protein kinase wzc isoform 1 (Escherichia coli K-12)
Ikaros family zinc finger protein 2 (mouse)
zinc finger protein Helios isoform B (mouse)
zinc finger protein Helios isoform A (mouse)
mothers against decapentaplegic homolog 3 isoform 1 (human)
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse)
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse)
long chain base biosynthesis protein 2 (mouse)
long chain base biosynthesis protein 2a (mouse)
serine-palmitoyl-CoA transferase 2 (mouse)
serine palmitoyltransferase 2 isoform 1 (mouse)
homeobox protein Meis2 isoform Meis2C (mouse)
homeobox protein Meis2 isoform Meis2A (mouse)
mothers against decapentaplegic homolog 5 isoform 1 (mouse)
mothers against decapentaplegic homolog 4 isoform 1 (mouse)
pituitary homeobox 2 isoform Ptx2B (mouse)
pituitary homeobox 2 isoform ARP1B (mouse)
pituitary homeobox 2 isoform BRX1B (mouse)
pituitary homeobox 2 isoform Ptx2C (mouse)
pituitary homeobox 2 isoform ARP1C (mouse)
pituitary homeobox 2 isoform BRX1A (mouse)
positive regulation of myoblast proliferation
pituitary homeobox 2 isoform Ptx2A (mouse)
pituitary homeobox 2 isoform ARP1A (mouse)
fumarate hydratase, mitochondrial isoform 1 (mouse)
fumarate hydratase isoform mitochondrial (mouse)
mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse)
vascular endothelial growth factor C isoform 1 (mouse)
positive regulation of cell-matrix adhesion
positive regulation of endopeptidase activity
cyclic nucleotide-gated channel alpha-1 isoform 1 (cow)
intracellular cyclic nucleotide activated cation channel complex
vascular endothelial growth factor A, long form isoform 2 (mouse)
vascular endothelial growth factor receptor 1 binding
positive regulation of endothelial cell proliferation
vascular endothelial growth factor A, long form isoform 3 (mouse)
vascular endothelial growth factor A, long form isoform 4 (mouse)
granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse)
GM-CSF receptor alpha subunit isoform 1 (mouse)
GM-CSF receptor alpha-chain isoform 1 (mouse)
granulocyte colony-stimulating factor receptor activity
granulocyte colony-stimulating factor binding
DNA-binding protein inhibitor ID-3 (human)
class B basic helix-loop-helix protein 25 (human)
ID-like protein inhibitor HLH 1R21 (human)
DNA-binding protein inhibitor ID-3 isoform 1 (human)
DNA-binding protein Ikaros isoform VI (mouse)
positive regulation of NK T cell differentiation
proprotein convertase subtilisin/kexin type 5 isoform PC5B (mouse)
proprotein convertase subtilisin/kexin type 5 isoform Long (mouse)
proprotein convertase subtilisin/kexin type 5 isoform PC5A (mouse)
proprotein convertase subtilisin/kexin type 5 isoform Short (mouse)
1-aminocyclopropane-1-carboxylate synthase 2 (Arabidopsis thaliana)
S-adenosyl-L-methionine methylthioadenosine-lyase 2 (Arabidopsis thaliana)
apoptosis regulator BAX isoform Alpha (mouse)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
galectin-3-binding protein isoform 1 (human)
calcium-activated potassium channel subunit alpha-1 isoform 1 (mouse)
calcium-activated potassium channel subunit alpha-1 isoform 4 (mouse)
calcium-activated potassium channel subunit alpha-1 isoform STREX-1 (mouse)
runt-related transcription factor 2 isoform 8 (mouse)
runt-related transcription factor 2 isoform 9 (mouse)
retinoblastoma-like protein 2 isoform 1 (human)
glutamate receptor, ionotropic, delta 2-interacting protein 1 (mouse)
voltage-gated inwardly rectifying potassium channel KCNH2 (human)
ether-a-go-go-related gene potassium channel 1 (human)
voltage-gated potassium channel subunit Kv11.1 (human)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A (human)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform B (human)
voltage-gated inwardly rectifying potassium channel KCNH2 isoform A-USO (human)
cell division cycle protein 20 homolog (human)
cell division cycle protein 16 homolog (human)
anaphase-promoting complex subunit 6 (human)
serine/threonine-protein kinase 4 (human)
mammalian STE20-like protein kinase 1 (human)
serine/threonine-protein kinase Krs-2 (human)
mitotic spindle assembly checkpoint protein MAD2A (human)
mitotic arrest deficient 2-like protein 1 (human)
Timing=interphase and mitosis. Target=PR:Q12834.
Rho-associated protein kinase 1 isoform 1 (human)
Note=Occurs after activation by PR:P61586 GTP bound
mothers against decapentaplegic homolog 4 isoform 1 (human)
short transient receptor potential channel 3 isoform 1 (human)
activin receptor type-2B isoform ActR-IIB2 (human)
activin receptor type-2B isoform ActR-IIBtrunc (human)
activin receptor type-2B isoform ActR-IIB1 (human)
activated leukocyte cell adhesion molecule (human)
bone morphogenetic protein receptor type-2 isoform 1 (human)
Note=BMP2 organism source not directly specified but, following the acknowledgements, the indicated source person (J Wozney) is listed as submitter of sequence for the human protein (see UniProtKB:P12643 and PMID:3201241)
Note=BMP7 organism source not directly specified but, following the acknowledgements, the indicated source person (K Sampath) is listed as submitter of sequence for the human protein (see UniProtKB:P18075 and PMID:2357959)
latent-transforming growth factor beta-binding protein 1 isoform Long (human)
latent-transforming growth factor beta-binding protein 1 isoform LTBP-1L (human)
regulator of G-protein signaling 9-binding protein (mouse)
intracellularly calcium-gated chloride channel activity
unique cartilage matrix-associated protein isoform 2 (mouse)
unique cartilage matrix-associated protein isoform 3 (mouse)
unique cartilage matrix-associated protein isoform 4 (mouse)
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (human)
PP2A B subunit isoform B56-alpha (human)
PP2A B subunit isoform PR61-alpha (human)
serine/threonine-protein kinase 38 (human)
mothers against decapentaplegic homolog 1 isoform 1 (human)
zinc finger homeobox protein 3 isoform 1 (human)
negative regulation of myoblast differentiation
zinc finger homeobox protein 3 isoform 2 (human)
positive regulation of myoblast differentiation
cyclic nucleotide-gated channel alpha-3 isoform 1 (human)
ligand-gated monoatomic ion channel activity
potassium voltage-gated channel subfamily A member 10 isoform 1 (human)
intracellularly cyclic nucleotide-activated monoatomic cation channel activity
anti-Muellerian hormone type-2 receptor isoform 1 (human)
potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse)
potassium voltage-gated channel subfamily A member 7 isoform Kv1.7L (mouse)
potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse)
potassium voltage-gated channel subfamily A member 7 isoform Kv1.7S (mouse)
A-kinase anchor protein 6 isoform beta (mouse)
A-kinase anchor protein 6 isoform alpha (mouse)
shaggy-related protein kinase eta (Arabidopsis thaliana)
protein BRASSINOSTEROID INSENSITIVE 2 (Arabidopsis thaliana)
protein ULTRACURVATA 1 (Arabidopsis thaliana)
shaggy-related protein kinase 21 (Arabidopsis thaliana)
positive regulation of protein export from nucleus
mitogen-activated protein kinase 6 (Arabidopsis thaliana)
ubiquitin carboxyl-terminal hydrolase CYLD isoform 4 (mouse)
negative regulation of T cell differentiation
YEATS domain-containing protein 2 isoform 1 (mouse)
pachytene checkpoint protein 2 homolog isoform 1 (mouse)
hepatoma-derived growth factor-related protein 2 isoform 1 (mouse)
hepatoma-derived growth factor-related protein 2 isoform a
hepatoma-derived growth factor-related protein 2 isoform 3 (mouse)
hepatoma-derived growth factor-related protein 2 isoform c
cell division cycle-associated protein 8 (human)
pluripotent embryonic stem cell-related gene 3 protein (human)
C-Jun-amino-terminal kinase-interacting protein 4 isoform 1 (mouse)
C-Jun-amino-terminal kinase-interacting protein 4 isoform 2 (mouse)
mitogen-activated protein kinase p38 binding
negative regulation of protein homodimerization activity
syntaxin-binding protein 5-like isoform 2 (mouse)
syntaxin-binding protein 5-like isoform Tomosyn-2 isoform m (mouse)
serologically defined breast cancer antigen NY-BR-85 (human)
SUN domain-containing protein 3 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 13 isoform 1 (mouse)
zinc finger protein 496 isoform 1 (mouse)
zinc finger protein 496 isoform 2 (mouse)
zinc finger protein 496 isoform 3 (mouse)
mitogen-activated protein kinase 12 (rice)
blast- and wound-induced MAP kinase 1 (rice)
positive regulation of plant-type hypersensitive response
nuclear factor of activated T-cells, cytoplasmic 2 isoform 2 (mouse)
nuclear factor of activated T-cells, cytoplasmic 2 isoform B (mouse)
nuclear factor of activated T-cells, cytoplasmic 2 isoform 3 (mouse)
nuclear factor of activated T-cells, cytoplasmic 2 isoform C (mouse)
nuclear factor of activated T-cells, cytoplasmic 2 isoform 4 (mouse)
nuclear factor of activated T-cells, cytoplasmic 2 isoform D (mouse)
PR domain zinc finger protein 1 isoform 1 (mouse)
negative regulation of B cell proliferation
positive regulation of B cell differentiation
PR domain zinc finger protein 1 isoform 2 (mouse)
negative regulation of lipopolysaccharide-mediated signaling pathway
BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse)
BAG family molecular chaperone regulator 1 isoform BAG-1 (mouse)
corticotropin-releasing factor receptor 2 isoform beta (mouse)
interleukin-15 receptor subunit alpha isoform 1 (mouse)
homeobox protein Meis1 isoform 1 (mouse)
homeobox protein Meis1 isoform Meis1A (mouse)
homeobox protein Meis1 isoform 2 (mouse)
homeobox protein Meis1 isoform Meis1B (mouse)
negative regulation of protein-containing complex assembly
activin receptor type-1-like isoform 1 (mouse)
receptor tyrosine-protein kinase erbB-4 (mouse)
proto-oncogene-like protein c-ErbB-4 (mouse)
RNA-binding protein FXR1 isoform E (mouse)
RNA-binding protein FXR1 isoform A (mouse)
RNA-binding protein FXR1 isoform D (mouse)
RNA-binding protein FXR1 isoform F (mouse)
RNA-binding protein FXR1 isoform G (mouse)
heat shock protein 105 kDa isoform HSP105-alpha (mouse)
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of apoptotic signaling pathway
heat shock protein 105 kDa isoform HSP105-beta (mouse)
positive regulation of protein tyrosine kinase activity
integrin alpha-6 isoform Alpha-6X1A (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 5' (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 3 (mouse)
potassium voltage-gated channel subfamily A member 5 isoform 3' (mouse)
endoplasmic reticulum membrane sensor NFE2L1 isoform Nrf1b (mouse)
nuclear factor erythroid 2-related factor 1 isoform 2 (mouse)
TGF-beta receptor type-2 isoform RII-2 (mouse)
TGF-beta receptor type-2 isoform RII-1 (mouse)
cyclic nucleotide-gated channel alpha-2 (mouse)
cyclic nucleotide-gated cation channel 2 (mouse)
mothers against decapentaplegic homolog 2 isoform Long (mouse)
mitogen-activated protein kinase 3 isoform 1 (mouse)
left-right determination factor 1 isoform 1 (mouse)
Bcl-2-like protein 1 isoform Bcl-X(L) (mouse)
Bcl-2-like protein 1 isoform Bcl-xL (mouse)
Bcl-2-like protein 1 isoform Bcl-X(S) (mouse)
Bcl-2-like protein 1 isoform Bcl-xS (mouse)
retinoblastoma-like protein 2 isoform 1 (mouse)
E3 ubiquitin-protein ligase SH3RF1 isoform 1 (mouse)
pro-neuregulin-1, membrane-bound isoform (mouse)
ZZ-type zinc finger-containing protein 3 isoform 1 (mouse)
retinoic acid receptor RXR-alpha isoform 2 (mouse)
coiled-coil domain-containing protein 66 isoform 1 (mouse)
post-embryonic retina morphogenesis in camera-type eye
mediator of RNA polymerase II transcription subunit 16 isoform 1 (mouse)
calcium/calmodulin-dependent protein kinase type II subunit delta (mouse)
calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1 (mouse)
calcium/calmodulin-dependent protein kinase type II subunit delta isoform delta 2 (mouse)
PHD finger protein 21A isoform 3 (mouse)
PHD finger protein 21A isoform BHC80-6(AIF2+5) (mouse)
transcription factor SPEECHLESS (Arabidopsis thaliana)
basic helix-loop-helix protein 98 (Arabidopsis thaliana)
bHLH transcription factor bHLH098 (Arabidopsis thaliana)
transcription factor EN 19 (Arabidopsis thaliana)
transient receptor potential cation channel subfamily V member 1 isoform 1 (mouse)
transient receptor potential cation channel subfamily V member 1 isoform Alpha (mouse)
mouse stress-inducible intra-cellular carbonic anhydrase isozyme VI
FH1/FH2 domain-containing protein 3 isoform FHOS2L (mouse)
zinc transporter ZIP4 isoform Long (mouse)
zinc ion transmembrane transporter activity
mediator of RNA polymerase II transcription subunit 26 isoform 1 (mouse)
transcription factor RFX4 isoform 1 (mouse)
transcription factor RFX4 isoform bRFX4 (mouse)
transcription factor RFX4 isoform RFX4_v3 (mouse)
negative regulation of dendrite development
positive regulation of dendrite development
mitotic checkpoint serine/threonine-protein kinase BUB1 beta (chicken)
Timing=spindle depolymerization (nocodazole) and lack of kinetochore tension (taxol).
heparan-sulfate 6-O-sulfotransferase 2 isoform 3 (mouse)
heparan sulfate 6-sulfotransferase activity
heparan sulfate proteoglycan biosynthetic process
SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 (mouse)
cation channel sperm-associated protein 3 (mouse)
cation channel sperm-associated protein 3 isoform 1 (mouse)
serine/threonine-protein kinase LMTK1 isoform 1 (mouse)
serine/threonine-protein kinase LMTK1 isoform 2 (mouse)
serine/threonine-protein kinase LMTK1 isoform 3 (mouse)
death-associated protein kinase 1 isoform 1 (mouse)
death-associated protein kinase 1 isoform Beta (mouse)
mediator of RNA polymerase II transcription subunit 23 isoform 1 (mouse)
deleted in lymphocytic leukemia 8 homolog (mouse)
brain-specific homeobox protein homolog isoform 1 (mouse)
brain-specific homeobox protein homolog isoform 2 (mouse)
methylcytosine dioxygenase TET3 isoform 1 (mouse)
DNA 5-methylcytosine dioxygenase activity
chromosomal 5-methylcytosine DNA demethylation, oxidation pathway
methylcytosine dioxygenase TET3 isoform 3 (mouse)
RNA binding protein fox-1 homolog 3 isoform 1 (mouse)
regulation of alternative mRNA splicing, via spliceosome
RNA binding protein fox-1 homolog 3 isoform 4 (mouse)
RNA binding protein fox-1 homolog 3 isoform 5 (mouse)
transient receptor potential cation channel subfamily A member 1 (mouse)
ankyrin-like with transmembrane domains protein 1 (mouse)
detection of mechanical stimulus involved in sensory perception of pain
detection of chemical stimulus involved in sensory perception of pain
transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse)
mothers against decapentaplegic homolog 3 isoform 1 (mouse)
amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 1 (mouse)
amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog
amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 2 (mouse)
zinc finger protein Eos isoform 1 (mouse)
zinc finger protein Eos isoform 2 (mouse)
ERI1 exoribonuclease 3 isoform 1 (mouse)
E3 SUMO-protein ligase PIAS2 isoform 1 (mouse)
E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)
E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)
regulation of osteoblast differentiation
E3 SUMO-protein ligase PIAS2 isoform 2 (mouse)
E3 SUMO-protein ligase PIAS2 isoform ARIP3 (mouse)
E3 SUMO-protein ligase PIAS2 isoform PIASx-alpha (mouse)
selection and upkeep of intraepithelial T-cells protein 2 isoform 5 (mouse)
transcriptional adapter 2-alpha isoform 1 (mouse)
lysine-specific histone demethylase 1B (mouse)
flavin-containing amine oxidase domain-containing protein 1 (mouse)
lysine-specific histone demethylase 2 (mouse)
lysine-specific histone demethylase 1B isoform 1 (mouse)
histone H3K4me/H3K4me2/H3K4me3 demethylase activity
transcription factor Ovo-like 2 isoform 1 (mouse)
transcription factor Ovo-like 2 isoform 2 (mouse)
superoxide-generating NADPH oxidase activity
mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog)
Target=PR:Q6DFD4. Target=PR:P79935. Kinase activity not required for interaction.
Kinase activity not required for interaction.
Kinase activity not required for interaction. Timing=throughout cell cycle and upon spindle disruption (nocodazole).
Timing=Mitosis and spindle disruption (nocodazole). Kinetochore localization requires Bub1 and is increased by Mad1.
solute carrier organic anion transporter family member 4A1 isoform 1 (mouse)
organic anion transmembrane transporter activity
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)
negative regulation of insulin receptor signaling pathway
ankyrin repeat and SOCS box protein 2 isoform 1 (mouse)
zinc finger CCCH-type antiviral protein 1 isoform 4 (mouse)
zinc finger CCCH-type antiviral protein 1 isoform ZAPS (mouse)
transient receptor potential cation channel subfamily V member 3 isoform A (mouse)
transient receptor potential cation channel subfamily V member 3 isoform 1 (mouse)
sperm-associated antigen 16 protein isoform 1 (mouse)
sperm-associated antigen 16 protein isoform SPAG16L (mouse)
interleukin-1 receptor-associated kinase 3 (mouse)
IL-1 receptor-associated kinase M (mouse)
inactive IL-1 receptor-associated kinase 3 (mouse)
negative regulation of toll-like receptor signaling pathway
interleukin-17 receptor C isoform 1 (mouse)
STE20-related kinase adapter protein beta isoform 1 (mouse)
NAD(P)H-hydrate epimerase isoform 1 (mouse)
anti-Muellerian hormone type-2 receptor isoform 1 (mouse)
anti-Mullerian hormone receptor activity
anti-Mullerian hormone receptor signaling pathway
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human)
negative regulation of interleukin-1-mediated signaling pathway
voltage-gated delayed rectifier potassium channel KCNH5 (human)
ether-a-go-go potassium channel 2 (human)
voltage-gated potassium channel subunit Kv10.2 (human)
cation channel sperm-associated protein 1 isoform 1 (human)
activin receptor type-1C isoform 4 (human)
activin receptor type-1C isoform Truncated (human)
transient receptor potential cation channel subfamily V member 3 isoform 1 (human)
outer kinetochore KNL1 complex subunit KNL1 (human)
ALL1-fused gene from chromosome 15q14 protein (human)
cancer susceptibility candidate gene 5 protein (human)
tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse)
negative regulation of interleukin-10 production
negative regulation of interleukin-12 production
transcriptional adapter 3 isoform 1 (mouse)
NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse)
histone H3K14 deacetylase activity, NAD-dependent
NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse)
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse)
degenerative spermatocyte homolog 2 (mouse)
sphingolipid delta-4 desaturase activity
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1 (mouse)
solute carrier organic anion transporter family member 3A1 isoform 1 (mouse)
oligopeptide transmembrane transporter activity
solute carrier organic anion transporter family member 3A1 isoform 2 (mouse)
sodium/hydrogen exchanger 8 isoform 1 (mouse)
transient receptor potential cation channel subfamily M member 8 (mouse)
long transient receptor potential channel 6 (mouse)
voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (rat)
potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (rat)
voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (rat)
potassium voltage-gated channel subfamily G member 3 isoform Kv10.1a (rat)
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse)
negative regulation of Rac protein signal transduction
negative regulation of Rho protein signal transduction
cell adhesion molecule 1 isoform 2 (mouse)
cell adhesion molecule 1 isoform c (mouse)
cell adhesion molecule 1 isoform 3 (mouse)
cell adhesion molecule 1 isoform b (mouse)
cell adhesion molecule 1 isoform 4 (mouse)
cell adhesion molecule 1 isoform d (mouse)
voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (human)
potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (human)
mediator of RNA polymerase II transcription subunit 17 isoform 1 (mouse)
phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform 1 (mouse)
negative regulation of extrinsic apoptotic signaling pathway
SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse)
binding between proteins from heterogeneous species; tubulin isotype not specified
positive regulation of receptor-mediated endocytosis
adhesion G-protein coupled receptor V1 (mouse)
monogenic audiogenic seizure susceptibility protein 1 (mouse)
very large G-protein coupled receptor 1 (mouse)
inner ear receptor cell stereocilium organization
positive regulation of DNA-binding transcription factor activity
ethylene-responsive transcription factor 6 (Arabidopsis thaliana)
ethylene-responsive element-binding factor 6 (Arabidopsis thaliana)
E3 ubiquitin-protein ligase TRIM41 isoform 2 (human)
Ras association domain-containing protein 5 isoform 2 (human)
solute carrier family 12 member 5 isoform 1 (mouse)
solute carrier family 12 member 5 isoform 2 (mouse)
transient receptor potential cation channel subfamily V member 6 (mouse)
elongator complex protein 2 isoform 1 (mouse)
mannan-binding lectin serine protease 2 isoform 1 (mouse)
mannan-binding lectin serine protease 2 isoform 2 (mouse)
glycine receptor subunit alpha-3 isoform Alpha-3L (mouse)
glycine receptor subunit alpha-3 isoform 1 (mouse)
dynein axonemal heavy chain 8 isoform 1 (mouse)
cation channel sperm-associated protein 1 (mouse)
fusion of sperm to egg plasma membrane involved in single fertilization
cation channel sperm-associated protein 1 isoform 1 (mouse)
sentrin-specific protease 2 isoform 1 (mouse)
negative regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator
sentrin-specific protease 2 isoform 2 (mouse)
sentrin-specific protease 2 isoform 3 (mouse)
mediator of RNA polymerase II transcription subunit 28 isoform 1 (mouse)
E3 ubiquitin-protein ligase SIAH1 isoform 1 (rat)
mediator of RNA polymerase II transcription subunit 6 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 15 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 1 isoform 1 (mouse)
cell adhesion molecule CEACAM2 isoform 2 (mouse)
cell adhesion molecule CEACAM2 isoform 3 (mouse)
glutamate receptor-interacting protein 1 isoform 2 (mouse)
regulator of nonsense transcripts 1 isoform 2 (human)
small conductance calcium-activated potassium channel protein 1 isoform 2 (human)
potassium voltage-gated channel subfamily B member 2 isoform 1 (human)
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 (Arabidopsis thaliana)
BRI1-associated receptor kinase 1 (Arabidopsis thaliana)
protein ELONGATED (Arabidopsis thaliana)
somatic embryogenesis receptor kinase 3 (Arabidopsis thaliana)
somatic embryogenesis receptor-like kinase 3 (Arabidopsis thaliana)
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 (Arabidopsis thaliana)
RAD51-associated protein 1 isoform 2 (human)
RAD51-associated protein 1 isoform 3 (human)
baculoviral IAP repeat-containing protein 7 isoform 1 (human)
baculoviral IAP repeat-containing protein 7 isoform Livin beta (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
aurora- and IPL1-like midbody-associated protein 1 (human)
serine/threonine-protein kinase 12 (human)
serine/threonine-protein kinase 5 (human)
serine/threonine-protein kinase aurora-B (human)
Target=PR:O60566. Target=PR:Q02224. Target=PR:Q13257. Target=PR:O43683.
delayed-rectifier potassium channel regulatory subunit KCNS1 isoform 1 (human)
voltage-gated delayed rectifier potassium channel KCNH8 (human)
ether-a-go-go-like potassium channel 3 (human)
voltage-gated potassium channel subunit Kv12.1 (human)
cation channel sperm-associated protein 2 isoform 1 (human)
cation channel sperm-associated protein 2 isoform Variant 2 (human)
Rab-3A-interacting protein isoform 1 (human)
Rab-3A-interacting protein isoform 2 (human)
mitotic checkpoint serine/threonine-protein kinase BUB1 sequence variant 1 (frog)
Timing=Meiosis I, Meiosis II, Mitosis (prophase, metaphase, anaphase).
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Max-binding protein MNT isoform 1 (human)
pituitary homeobox 2 isoform Ptx2B (human)
pituitary homeobox 2 isoform ARP1B (human)
pituitary homeobox 2 isoform Ptx2C (human)
pituitary homeobox 2 isoform ARP1C (human)
pituitary homeobox 2 isoform Ptx2A (human)
pituitary homeobox 2 isoform ARP1A (human)
mothers against decapentaplegic homolog 5 isoform 1 (human)
calcitonin gene-related peptide 1 (mouse)
negative regulation of nervous system process
mediator of RNA polymerase II transcription subunit 24 isoform 1 (mouse)
pre-mRNA-processing factor 19 isoform 2 (mouse)
positive regulation of astrocyte differentiation
electron transfer flavoprotein subunit alpha, mitochondrial isoform 1 (mouse)
MAP3K12-binding inhibitory protein 1 isoform 1 (mouse)
Bcl-2-binding component 3 isoform 1 (mouse)
double-stranded RNA-specific adenosine deaminase isoform 1 (mouse)
double-stranded RNA adenosine deaminase activity
negative regulation of viral genome replication
double-stranded RNA-specific adenosine deaminase isoform 2 (mouse)
double-stranded RNA-specific adenosine deaminase isoform 3 (mouse)
double-stranded RNA-specific adenosine deaminase isoform 4 (mouse)
carbohydrate-responsive element-binding protein isoform 1 (mouse)
carbohydrate-responsive element-binding protein isoform Zeta (mouse)
partitioning defective 3 homolog isoform 3 (mouse)
Bcl-2-binding component 3 isoform 1 (human)
Bcl-2-binding component 3 isoform PUMA alpha (human)
protein decapping 5 (Arabidopsis thaliana)
mediator of RNA polymerase II transcription subunit 21 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 4 isoform 1 (mouse)
regulation of insulin secretion involved in cellular response to glucose stimulus
E3 ubiquitin-protein ligase SMURF1 (mouse)
HECT-type E3 ubiquitin transferase SMURF1 (mouse)
SMAD ubiquitination regulatory factor 1 (mouse)
SMAD-specific E3 ubiquitin-protein ligase 1 (mouse)
E3 ubiquitin-protein ligase SMURF1 isoform Short (mouse)
mediator of RNA polymerase II transcription subunit 31 isoform 1 (mouse)
putative RNA-binding protein Luc7-like 1 isoform 1 (mouse)
putative RNA-binding protein Luc7-like 1 isoform 2 (mouse)
ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 1 (mouse)
ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 2 (mouse)
mediator of RNA polymerase II transcription subunit 18 isoform 1 (mouse)
SUN domain-containing protein 1 isoform m5 (mouse)
SUN domain-containing protein 1 isoform eta (mouse)
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (mouse)
mitochondrial peptide methionine sulfoxide reductase isoform 1 (mouse)
mitochondrial peptide methionine sulfoxide reductase isoform 2 (mouse)
mediator of RNA polymerase II transcription subunit 8 isoform 1 (mouse)
metalloendopeptidase OMA1, mitochondrial isoform 1 (mouse)
SAGA-associated factor 29 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 27 isoform 1 (mouse)
high mobility group nucleosome-binding domain-containing protein 3 isoform 1 (mouse)
high mobility group nucleosome-binding domain-containing protein 3 isoform 2 (mouse)
DNA repair protein RAD51 homolog 4 isoform d4 (mouse)
DNA repair protein RAD51 homolog 4 isoform d3 (mouse)
DNA repair protein RAD51 homolog 4 isoform d2 (mouse)
DNA repair protein RAD51 homolog 4 isoform d7 (mouse)
DNA repair protein RAD51 homolog 4 isoform d1 (mouse)
DNA repair protein RAD51 homolog 4 isoform d6 (mouse)
transient receptor potential cation channel subfamily V member 4 (mouse)
transient receptor potential protein 12 (mouse)
vanilloid receptor-like channel 2 (mouse)
vanilloid receptor-like protein 2 (mouse)
vanilloid receptor-related osmotically-activated channel (mouse)
regulation of response to osmotic stress
transient receptor potential cation channel subfamily V member 4 isoform A (mouse)
transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)
transcription factor 20 isoform 1 (mouse)
transcription factor 20 isoform 2 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 1 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform V (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 3 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform VI (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 4 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform VII (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 5 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform VIII (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 6 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform IV (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 7 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform III (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 8 (mouse)
small conductance calcium-activated potassium channel protein 1 isoform II (mouse)
small conductance calcium-activated potassium channel protein 1 isoform 9 (mouse)
regulating synaptic membrane exocytosis protein 2 isoform 1 (mouse)
intercellular adhesion molecule 4 isoform 1 (mouse)
intercellular adhesion molecule 4 isoform 2 (mouse)
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse)
inositol-polyphosphate 5-phosphatase activity
phosphatidylinositol trisphosphate phosphatase activity
general transcription factor II-I isoform 1 (mouse)
general transcription factor II-I isoform 2 (mouse)
general transcription factor II-I isoform 4 (mouse)
mitogen-activated protein kinase binding
small conductance calcium-activated potassium channel protein 2 isoform 1 (human)
serine/threonine-protein kinase PLK3 (human)
cytokine-inducible serine/threonine-protein kinase (human)
E3 ubiquitin-protein ligase SMURF2 (human)
HECT-type E3 ubiquitin transferase SMURF2 (human)
SMAD ubiquitination regulatory factor 2 (human)
SMAD-specific E3 ubiquitin-protein ligase 2 (human)
regulation of transforming growth factor beta receptor signaling pathway
transient receptor potential cation channel subfamily V member 4 isoform A (human)
transient receptor potential cation channel subfamily V member 4 isoform 1 (human)
transient receptor potential cation channel subfamily V member 4 isoform B (human)
transient receptor potential cation channel subfamily V member 4 isoform 2 (human)
transient receptor potential cation channel subfamily V member 4 isoform OTRPC4beta (human)
transient receptor potential cation channel subfamily V member 4 isoform C (human)
transient receptor potential cation channel subfamily V member 4 isoform 4 (human)
transient receptor potential cation channel subfamily V member 4 isoform D (human)
transient receptor potential cation channel subfamily V member 4 isoform 5 (human)
transient receptor potential cation channel subfamily V member 4 isoform E (human)
transient receptor potential cation channel subfamily V member 4 isoform 6 (human)
E3 ubiquitin-protein ligase SMURF1 (human)
HECT-type E3 ubiquitin transferase SMURF1 (human)
SMAD ubiquitination regulatory factor 1 (human)
SMAD-specific E3 ubiquitin-protein ligase 1 (human)
E3 ubiquitin-protein ligase SMURF1 isoform Short (human)
short transient receptor potential channel 7 (human)
histone acetyltransferase KAT2B isoform 1 (mouse)
mothers against decapentaplegic homolog 9 isoform 1 (mouse)
negative regulation of actin filament polymerization
sodium channel protein type 5 subunit alpha isoform 1 (mouse)
cyclic nucleotide-gated channel alpha-3 isoform m1 (mouse)
cyclic nucleotide-gated channel beta-3 isoform 1 (mouse)
intracellularly cGMP-activated cation channel activity
potassium voltage-gated channel subfamily KQT member 5 isoform 1 (mouse)
potassium voltage-gated channel subfamily KQT member 4 (mouse)
potassium channel subunit alpha KvLQT4 (mouse)
voltage-gated potassium channel subunit Kv7.4 (mouse)
cold shock domain-containing protein A (mouse)
Y-box-binding protein 3 isoform 1 (mouse)
Y-box-binding protein 3 isoform 2 (mouse)
LIM domain-binding protein 3 isoform 1 (mouse)
LIM domain-binding protein 3 isoform 6 (mouse)
CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana)
protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)
SNF1-related kinase 3.11 (Arabidopsis thaliana)
Target=PR:Q8LAS7. Evidence=ECO:0000181.
hydrogen peroxide mediated signaling pathway
protein BRASSINAZOLE-RESISTANT 2 (Arabidopsis thaliana)
protein BIN2 SUBSTRATE 1 (Arabidopsis thaliana)
protein BRI1-EMS-SUPPRESSOR 1 (Arabidopsis thaliana)
C-type lectin domain family 4 member L (human)
dendritic cell-specific ICAM-3-grabbing non-integrin 1 (human)
Note=DC-SIGN seems critical for whether HIV is bound and targeted to the endolysosomal pathway; binding between proteins from heterogeneous species
diablo IAP-binding mitochondrial protein isoform 1 (human)
potassium voltage-gated channel subfamily KQT member 5 isoform 1 (human)
potassium voltage-gated channel subfamily KQT member 5 isoform 2 (human)
potassium voltage-gated channel subfamily KQT member 5 isoform 3 (human)
WW domain-containing oxidoreductase isoform 1 (human)
WW domain-containing oxidoreductase isoform FOR II (human)
WW domain-containing oxidoreductase isoform FOR2 (human)
WW domain-containing oxidoreductase isoform WWOX v8 (human)
WW domain-containing oxidoreductase isoform WWOXv1 (human)
A-type voltage-gated potassium channel KCND2 isoform 1 (human)
long-chain-fatty-acid--CoA ligase 4 isoform 1 (mouse)
short transient receptor potential channel 4 (mouse)
capacitative calcium entry channel Trp4 (mouse)
receptor-activated cation channel TRP4 (mouse)
short transient receptor potential channel 4 isoform alpha (mouse)
tumor protein p53-inducible nuclear protein 1 isoform 2 (mouse)
tumor protein p53-inducible nuclear protein 1 isoform SIP18 (mouse)
positive regulation of apoptotic signaling pathway
amyloid beta precursor protein binding family B member 1 isoform 1 (mouse)
amyloid beta A4 precursor protein-binding family B member 1 isoform 1 (mouse)
G protein-coupled photoreceptor activity
G protein-coupled opsin signaling pathway
unconventional myosin-IXb isoform 1 (mouse)
unconventional myosin-IXb isoform 3 (mouse)
unconventional myosin-IXb isoform C (mouse)
KH domain-containing RNA-binding protein QKI isoform 6 (mouse)
Toll-interacting protein isoform 1 (mouse)
core histone macro-H2A.1 isoform 1 (mouse)
mediator of RNA polymerase II transcription subunit 20 isoform 1 (mouse)
bone morphogenetic protein 10 isoform 1 (mouse)
short transient receptor potential channel 2 (mouse)
short transient receptor potential channel 2 isoform 1 (mouse)
short transient receptor potential channel 2 isoform A (mouse)
short transient receptor potential channel 2 isoform 2 (mouse)
short transient receptor potential channel 2 isoform B (mouse)
short transient receptor potential channel 2 isoform 3 (mouse)
short transient receptor potential channel 2 isoform Alpha (mouse)
short transient receptor potential channel 2 isoform 4 (mouse)
short transient receptor potential channel 2 isoform Beta (mouse)
1-aminocyclopropane-1-carboxylate synthase 6 (Arabidopsis thaliana)
S-adenosyl-L-methionine methylthioadenosine-lyase 6 (Arabidopsis thaliana)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform r1 (rabbit)
RING-box protein 2 isoform SAG-v (human)
short transient receptor potential channel 4 isoform alpha (human)
short transient receptor potential channel 4 isoform beta (human)
ribosomal protein S6 kinase beta-2 isoform 1 (human)
small conductance calcium-activated potassium channel protein 3 isoform 1 (human)
A-type voltage-gated potassium channel KCND3 isoform 1 (human)
potassium voltage-gated channel subfamily D member 3 isoform KCND3L (human)
potassium voltage-gated channel subfamily D member 3 isoform Long (human)
A-type voltage-gated potassium channel KCND3 isoform 2 (human)
potassium voltage-gated channel subfamily D member 3 isoform KCND3S (human)
potassium voltage-gated channel subfamily D member 3 isoform Short (human)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (human)
brain cyclic nucleotide-gated channel 2 (human)
voltage-gated delayed rectifier potassium channel KCNH4 isoform 1 (human)
serine/threonine-protein kinase STK11 isoform 1 (mouse)
serine/threonine-protein kinase STK11 isoform 2 (mouse)
sterol regulatory element-binding protein 1 isoform 1 (mouse)
sterol regulatory element-binding protein 1 isoform 3 (mouse)
S-phase kinase-associated protein 1 isoform 1 (mouse)
intrinsic apoptotic signaling pathway in response to oxidative stress
short transient receptor potential channel 7 isoform 1 (mouse)
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform 1 (human)
receptor-interacting serine/threonine-protein kinase 3 (human)
interleukin-1 receptor-associated kinase 3 isoform 1 (human)
mitotic spindle assembly checkpoint protein MAD1 (human)
mitotic arrest deficient 1-like protein 1 (human)
mitotic checkpoint MAD1 protein homolog (human)
CX3C chemokine receptor 1 isoform 1 (mouse)
microglial cell activation involved in immune response
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of smoothened signaling pathway
suppressor of fused homolog isoform 1 (mouse)
suppressor of fused homolog isoform 4 (mouse)
suppressor of fused homolog isoform SU(FU)-XL (mouse)
A-type voltage-gated potassium channel KCND2 isoform 1 (mouse)
ribosomal protein S6 kinase beta-2 isoform 1 (mouse)
STE20/SPS1-related proline-alanine-rich protein kinase isoform 1 (mouse)
C-C motif chemokine 27 isoform 1 (mouse)
positive regulation of T cell chemotaxis
C-C motif chemokine 27 isoform 2 (mouse)
neuroepithelial cell-transforming gene 1 protein isoform 1 (mouse)
neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse)
positive regulation of substrate adhesion-dependent cell spreading
methyl-CpG-binding protein 2 isoform 1 (mouse)
methyl-CpG-binding protein 2 isoform beta
methyl-CpG-binding protein 2 isoform 2 (mouse)
methyl-CpG-binding protein 2 isoform alpha
TSC22 domain family protein 3 isoform 1 (mouse)
negative regulation of skeletal muscle tissue development
TSC22 domain family protein 3 isoform 4 (mouse)
Long glucocorticoid-induced leucine zipper protein (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform 10 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.10 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform 11 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.11 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform 12 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform 9 (mouse)
potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.9 (mouse)
anti-Muellerian hormone type-2 receptor isoform Delta2 (mouse)
anti-Muellerian hormone type-2 receptor isoform 2 (mouse)
negative regulation of anti-Mullerian hormone signaling pathway
anti-Muellerian hormone type-2 receptor isoform Delta9/10 (mouse)